Skin Microbiome

Moreau, Magali; Zhen, Yaxian

doi:10.1002/9781119676881.ch8

Cited by 2 publications

(3 citation statements)

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“…Panthenol, a provitamin B5 derivative, is recognized for its moisturizing, soothing, and skin barrier‐enhancing properties 6 . Prebiotics, non‐digestible fibers that promote the growth of beneficial bacteria, and probiotic lysates, such as Aqua Posae Filiformis (APF), derived from the cell walls of probiotic bacteria, have been suggested to help restore skin microbiome balance, modulate immune responses, and reduce inflammation 7–9 …”

Section: Introductionmentioning

confidence: 99%

“…6 Prebiotics, non-digestible fibers that promote the growth of beneficial bacteria, and probiotic lysates, such as Aqua Posae Filiformis (APF), derived from the cell walls of probiotic bacteria, have been suggested to help restore skin microbiome balance, modulate immune responses, and reduce inflammation. [7][8][9] This study aims to evaluate the efficacy and safety of a cream composed of panthenol, a blend of prebiotics, and probiotic lysate in improving symptoms of facial sensitive skin. The intended mechanisms of action include barrier repair, restoration of skin microbiome balance, immune regulation, and reduction of inflammation.…”

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confidence: 99%

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Efficacy and safety of a cream containing panthenol, prebiotics, and probiotic lysate for improving sensitive skin symptoms

Zhang,

Kerob,

Zhang

et al. 2024

Skin Research and Technology

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BackgroundSensitive skin is a common condition affecting a significant proportion of the population, and there is a growing demand for effective and safe management.AimTo evaluate the efficacy and safety of a cream containing panthenol, prebiotics, and probiotic lysate as an optimal care for facial sensitive skin.MethodsA total of 110 participants (64 in group A and 46 in group B) with facial sensitive skin applied the cream twice daily for 28 days. Group A evaluated their sensitive skin, product efficacy, and product use experience at D0 (15 min), D1, D14, and D28. In group B, skin barrier function‐related indicators were measured at baseline and on D1, D7, D14, and D28. Dermatologists evaluated tolerance for all participants.ResultsAfter 28 days of use, in group A, 100% of participants reported mildness and comfort with product use. Participants demonstrated significant improvements in skin barrier function‐related indicators, including increased stratum corneum moisture content, reduced erythema index, elevated sebum content, decreased trans‐epidermal water loss, and diminished skin redness parameter a* value (all p < 0.05). Dermatologist evaluations revealed excellent tolerance among all participants.ConclusionThe panthenol‐enriched cream with prebiotics and probiotic lysate exhibited substantial clinical efficacy in ameliorating facial sensitive skin conditions, coupled with a high safety profile.

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Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

Efficacy and safety of a cream containing panthenol, prebiotics, and probiotic lysate for improving sensitive skin symptoms

Zhang,

Kerob,

Zhang

et al. 2024

Skin Research and Technology

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“…It follows that natural selection does not appear to have played a role in protecting human skin against the aforementioned numerous and nefarious parasites, bites, and damages. The complexity of human skin continues to be brought to the fore with the rising fragmentation of biology specialties (Moreau & Zhen, 2022;Sore & Lynch, 2022). No wonder recent research has determined that the mechanisms of natural selection could not and should not be reducible to melanin production that renders human skin dark/black.…”

Section: Human Skinmentioning

confidence: 99%

Toward a Synopsis of the Challenges Facing Mainstream Interpretations of Skin Pigmentation in Humans

Cibangu¹

2023

IJB

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When traditional or mainstream interpretations of skin pigmentation in humans were proposed, not much data was available about the anatomy of human skin in particular and pigment research in general. The most popular and influential thesis put forth to date to justify the evolution of skin pigmentation is the thesis that skin pigmentation grew out of a natural adaptation of Homo sapiens skin to scorching conditions of fiery heat faced with by Homo sapiens individuals in equatorial regions of Africa. It is thereby argued that peak UVR [ultraviolet rays] environments encountered in equatorial/savannah climate caused an eccrine gland production to offset the overheating of skin during the high physical activity of hunting exerted by Homo sapiens persons. However, with human anatomy increasingly becoming the object of scrutiny from various fronts of biology, newer insights have given rise to significant blind spots vis-à-vis traditional explanations of black skin pigmentation. The present paper takes stock of the major challenges afflicting existing characterizations of human skin evolution. Paths for future research of skin/pigment are suggested. The paper aims to lay out a follow-up on and/or synopsis of recurrent challenges that the space of pigment research has accumulated over the years, giving way to long due synergies. In a world supersensitive to racial equality and dignity, the paper furnishes concerned researchers and policy makers with a much-needed contribution to inquiry into dark- and black-skinned peoples.

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Skin Microbiome

Cited by 2 publications

References 84 publications

Efficacy and safety of a cream containing panthenol, prebiotics, and probiotic lysate for improving sensitive skin symptoms

Efficacy and safety of a cream containing panthenol, prebiotics, and probiotic lysate for improving sensitive skin symptoms

Toward a Synopsis of the Challenges Facing Mainstream Interpretations of Skin Pigmentation in Humans

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