Skin Manifestations of Giant-Cell. Arteritis.

Kinmont, P.D.C.; McCallum, Dugald

doi:10.1111/j.1365-2133.1964.tb14533.x

Cited by 56 publications

(14 citation statements)

References 18 publications

(1 reference statement)

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“…Temporal arteritis has also been associated with extreme ear pain (Aui-Aree et al, 2010). Other cutaneous conditions and manifestations with which temporal arteritis has had rare associations include psoriatic arthritis, scalp abscess, scalp ulceration with necrosis, butterfly rash of the face, tongue changes, gangrene or ulcers of the leg, purpura and ecchymoses, urticaria, edema, lividity, tender nodules, hyperpigmentation, tortuous arteries, and supravascular pallor (Aui-Aree et al, 2010, Baum et al, 1982, Corli et al, 2015, Kinmont and McCallum, 1964). …”

Section: Discussionmentioning

confidence: 99%

Infiltrated papules on the trunk and headaches: A case of actinic granuloma and a review of the literature

Parikh

Que

Holmes

et al. 2015

International Journal of Women's Dermatology

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Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomitant temporal arteritis. Our case and review of the literature emphasize the association between actinic granuloma and temporal arteritis, a serious inflammatory condition that could lead to blindness if misdiagnosed.

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Section: Discussionmentioning

confidence: 99%

Infiltrated papules on the trunk and headaches: A case of actinic granuloma and a review of the literature

Parikh

Que

Holmes

et al. 2015

International Journal of Women's Dermatology

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“…Like sarcoidosis, vasculitis can represent relatively benign, single‐organ (cutaneous) disease, or a systemic, multiorgan disease with poor prognosis . Sarcoidal granulomas associated with cutaneous vasculitis are a rare event, but they have been documented in the setting of granulomatous vasculitis (GV) and leukocytoclastic vasculitis (LCV) …”

mentioning

confidence: 99%

Circumscribed cicatricial alopecia due to localized sarcoidal granulomas and single‐organ granulomatous arteritis: a case report and systematic review of sarcoidal vasculitis

et al. 2015

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Vasculitis associated with sarcoid granulomas is an uncommon phenomenon. A 72-year-old female presented with an expanding region of circumscribed alopecia and scalp atrophy of 2 months duration. Biopsy showed non-caseating granulomas, dermal thinning, loss of follicles, fibrosis and muscular vessels disrupted by mixed lymphocyte, macrophage and giant-cell infiltrates. Affected vessels had loss and fragmentation of the elastic lamina, fibrous replacement of their walls and luminal stenosis (endarteritis obliterans). Dermal and vascular advential intralymphatic granulomas and lymphangiectases were found by D2-40 expression, suggesting lymphatic obstruction and poor antigen clearance. No evidence of a post-zoster eruption, systemic sarcoidosis or systemic giant-cell arteritis was found. Two years later, prednisone had halted - but not reversed - progression of her alopecia. Review of the literature showed two types of vasculitis associated with sarcoid granulomas: (i) acute, self-limited leukocytoclastic vasculitis and (ii) chronic granulomatous vasculitis (GV). Persistence of non-degradable material or antigen contributes to the pathogenesis of granulomatous inflammation. In this case, lymphatic obstruction probably impeded clearance of nonimmunologic and/or immunologic stimuli permitting and sustaining the development of sarcoid granulomas and sarcoid GV, ultimately causing scarring alopecia and cutaneous atrophy.

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“…Calcification in the area of the temporal artery has previously been described in giant cell arteritis. 5 Erythema nodosum has been reported to occur in association with Takayasu's arteritis, an idiopathic inflammatory process with a predilection for the aortic arch and its branches, occurring primarily in young women of oriental extraction. '4 15 In one patient with Takayasu's arteritis and skin lesions suggestive of erythema nodosum a biopsy of a nodule showed 'lesions of the small vessels of the subcutis which were reminiscent of polyarteritis nodosa'.…”

Section: Pathologymentioning

confidence: 99%