Skin involvement as the presenting sign of internal carcinoma

Lookingbill, Donald P.; Spangler, Nancy; Sexton, F. Mack

doi:10.1016/0190-9622(90)70002-y

Cited by 536 publications

(501 citation statements)

References 17 publications

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“…Ulceration occurs in approximately 10 % of nodules to the skin [6]. Skin involvement as the presenting sign of a silent internal malignancy is an even rarer event occurring in approximately 0.8 % [7]. The occurrence of cutaneous metastatic disease from colorectal cancer is uncommon and typically signifies widespread disease with poor prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…The identification of cutaneous metastasis from a visceral malignancy is an ominous finding which usually signifies widespread disease and portends a poor prognosis [1,9]. Lookingbill et al [7] in a retrospective study of 4,020 patients found that after recognition of skin metastases, mean survival ranged from 1 to 34 months depending on the primary tumor. An average survival of 18 months was noted in patients with skin metastasis from colorectal carcinoma [7].…”

Section: Discussionmentioning

confidence: 99%

“…Lookingbill et al [7] in a retrospective study of 4,020 patients found that after recognition of skin metastases, mean survival ranged from 1 to 34 months depending on the primary tumor. An average survival of 18 months was noted in patients with skin metastasis from colorectal carcinoma [7]. Schoenlaub et al [17] retrospectively reviewed 200 cases of patients with evidence of cutaneous metastasis from a visceral primary and found the median survival to be 6.5 months.…”

Section: Discussionmentioning

confidence: 99%

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Metastasis of Rectal Carcinoma in Testes and Skin: Case Series

Kushwaha

Sonkar

Verma

et al. 2013

Indian J Surg Oncol

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Metastasis of Rectal Carcinoma in Testes and Skin: Case Series

Kushwaha

Sonkar

Verma

et al. 2013

Indian J Surg Oncol

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“…Although there is no consensus in the literature regarding the frequency of cutaneous metastases, they are most commonly related to primary breast and lung tumors, the chest and abdomen being the sites that are most commonly affected by this type of dissemination. (5,11,12) Skin lesions can present in different forms, the most common being hard, painless, rapidly growing nodules that adhere to deep planes and are skin-colored or slightly erythematous, with or without ulcerations. As a manifestation of breast and oral cavity cancers, skin lesions can present as nodules of sclerotic and inflammatory appearance; they can also present as a direct extension of the primary tumor.…”

Section: Discussionmentioning

confidence: 99%

Metástase cutânea como primeira manifestação de adenocarcinoma pulmonar

et al. 2011

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associated with a worse prognosis. (6,7) Physicians who deal with this pathology should be on the alert for the possibility of cutaneous metastasis as the initial manifestation of lung cancer. Case reportA 58-year-old waiter who had quit smoking 9 years prior (smoking history, 40 pack-years) was referred for medical oncology consultation because of an epigastric mass. The patient presented with a history of COPD with severe IntroductionAnnually, metastatic disease accounts for over half of the new cases of lung cancer in Europe.(1) In Portugal, the estimated annual incidence is approximately 2,500 cases, and mortality among such cases is nearly 100%, lung cancer being the leading cause of cancer death.(1,2) To date, there has been no evidence of an effective method for population screening, (3) smoking cessation being fundamental to reducing the number of cases. AbstractWe report the case of a 58-year-old male patient who was referred for oncology consultation due to an epigastric mass that had been growing rapidly for three months. Diagnostic investigation revealed that the mass was a metastasis of stage IV lung adenocarcinoma. The patient received five cycles of chemotherapy with cisplatin and gemcitabine as a first-line treatment, which was interrupted due to major adverse events. Although the pulmonary disease stabilized, the cutaneous disease progressed. The patient then received pemetrexed as a secondline chemotherapy, together with concurrent external radiotherapy, which was well tolerated. There was complete remission of the epigastric mass. However, the patient died three months after the treatment. Here, we emphasize the importance of a multidisciplinary approach and of its role in individualizing the treatment.

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“…It is difficult to determine accurately the number of patients being treated for malignant fungating wounds. However it is thought that over 5% of patients with cancer develop a malignant fungating wound [10]. In Switzerland the prevalence reported by nurses was 6.6% [17].…”

Section: Background and Contextmentioning

confidence: 99%

Caring for a loved one with a malignant fungating wound

Probst

Arber

Trojan

et al. 2012

Support Care Cancer

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Purpose: Caring for a loved one with a malignant fungating wound is very challenging and causes extreme physical and psychological distress. The aim of this study was to explore the experiences of carers who care for a loved one with a fungating breast wound.Method: To explore the lived experiences of carers a methodological framework using Heideggerian hermeneutic phenomenology and semi-structured interviews was used. Seven carers were interviewed from January until November 2009.Results: Having to deal with a situation of a loved one with a visible cancer was hard for all the carers.The visibility of the cancer was one of the most shocking aspects to deal with from the perspective of the patient and the carer. The presence of the visible wound and a cancer at an advanced stage contributed to a change in the relationship and extreme suffering for both the patient and the carer.Despite many problems such as wound odour and copious discharge from the wound, which was difficult to control carers did their best to help their loved one with the wound. Gradually the wound became the centre of the patient and carer's life and a great deal of time was spent trying to control the wound symptoms. All carers managed the wound on their own without help and advice from health care practitioners. For all of them it was a major burden and they felt isolated.Conclusion: This study contributes to an understanding that the care of women and their carers needs strategies that are integrated in palliative wound care, that takes a holistic and empathic approach that responds to patients and carers psychosocial and emotional needs and a practical need for information to help carers assist in managing the wound related symptoms.

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Skin involvement as the presenting sign of internal carcinoma

Cited by 536 publications

References 17 publications

Metastasis of Rectal Carcinoma in Testes and Skin: Case Series

Metastasis of Rectal Carcinoma in Testes and Skin: Case Series

Metástase cutânea como primeira manifestação de adenocarcinoma pulmonar

Caring for a loved one with a malignant fungating wound

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