Skin Hypersensitivity to Phenylhydrazin Hydrochlorid

Wright, Irving S.; Joyner, Edmund N.

doi:10.1097/00000441-193005000-00011

Cited by 2 publications

(1 citation statement)

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“…Patch-testing with the dry powder moistened with water produced positive skin reactions in the patient, indicating skin sensitivity to phenylhydrazine [Downing 1937]. Wright and Joyner [1930] reported a case of skin hypersensitivity following occupational exposures to phenylhydrazine, phenylhydrazine salts, or a mixture of phenylhydrazine hydrochloride and sodium acetate; however following a series of patch tests with potential compounds, this patient was found to be hypersensitive to phenylhydrazine hydrochloride, but not pure phenylhydrazine. Frost and Hjorth [1959] reported cross-reactivity between phenylhydrazine and hydrazine salts when a patient was patch-tested with aqueous solutions of phenylhydrazine (0.2%).…”

Section: Immune-mediated Responses (Sk: Sen)mentioning

confidence: 99%

NIOSH skin notation (SK) profiles: phenylhydrazine [CAS No. 100-63-0].

Dotson¹,

Hudson²,

Frasch³

et al. 2014

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This Skin Notation Profile provides the SK assignments and supportive data for phenylhydrazine. In particular, this document evaluates and summarizes the literature describing the hazard potential of the substance and its assessment according to the scientific rationale and framework outlined in CIB 61. In meeting this objective, this Skin Notation Profile intends to inform the audience-mostly occupational health practitioners, researchers, policy-and decision-makers, employers, and workers in potentially hazardous workplaces-so that improved risk-management practices may be developed to better protect workers from the risks of skin contact with the chemicals of nterest.

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Section: Immune-mediated Responses (Sk: Sen)mentioning

confidence: 99%