Skin conductance reaction (SCR)-habituation test, an elementary model of anxiety as a tool to assess anxiogenic activities of some drugs

Quermonne, M. A.; Nammathao, Bounsay; Louchahi‐Raoul, J.; Marcy, R

doi:10.1016/0278-5846(93)90050-3

Cited by 9 publications

(4 citation statements)

References 7 publications

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“…Increased muscle tension (particularly the frontalis muscle, which has been proposed to primarily reflect affective states [9] ) and altered electrodermal [10,11] responses to stressors have consistently been found in patients with anxiety disorders and have been correlated to catecholaminergic tone [9,12]. Hyperarousal, as well as muscular and autonomic symptoms, frequently accompany the typical increased apprehension in GAD.…”

Section: Introductionmentioning

confidence: 99%

Venlafaxine Versus Applied Relaxation for Generalized Anxiety Disorder: A Randomized Controlled Study on Clinical and Electrophysiological Outcomes

et al. 2014

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Some components of generalized anxiety disorder, such as physical symptoms, are thought to reflect autonomic nervous system arousal. This study primarily assessed the relationships between psychophysiological and clinical measures using venlafaxine extended release or applied relaxation, and secondarily, the impact of combination treatment in patients not remitting after 8 weeks. Fifty-eight patients were randomly assigned to 8 weeks of treatment with either venlafaxine or applied relaxation (Phase I). Non-remitted patients received combination treatment for an additional 8 weeks (Phase II). Assessments included the Hamilton Anxiety Scale (HAM-A), Beck Depression Inventory, Penn State Worry Questionnaire and the Stroop Color-Word Task coupled with electrophysiological measures (skin conductance and frontalis electromyography (EMG)). In Phase 1, a time effect was found for the clinical and skin conductance measures. Thirteen patients from each group were in remission. In Phase 2, seven additional patients remitted. Baseline psychophysiological measures were not associated with baseline clinical variables or with clinical outcomes. Independently of treatment allocation, a reduction in frontal EMG values at week 4 was significantly associated with a decrease in HAM-A scores at week 8. At week 4, responders from the applied relaxation group had lower electrophysiological activity than the venlafaxine group. Baseline psychophysiological measures were not linked with clinical measures at study inclusion or with treatment response. Frontal EMG response at week 4 is a possible predictor of treatment response. Treatment combination enhances treatment response after initial failure.

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Section: Introductionmentioning

confidence: 99%

Venlafaxine Versus Applied Relaxation for Generalized Anxiety Disorder: A Randomized Controlled Study on Clinical and Electrophysiological Outcomes

et al. 2014

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“…Les états anxieux ont été associés à des modifications de la conductance cutanée (Fredrikson et al, 1976 ;Fredrikson et Ohman, 1979 ;Naveteur et Baque, 1988 ;Quermonne et al, 1993) et des réponses cardiovasculaires (Carrillo et al, 2001) à des stresseurs. L'élévation de la tension musculaire, et en particulier du muscle frontal, a été l'observation la plus constante (Hoehn-Saric et al, 1989a), et il semble refléter principalement des états affectifs alors que la tension d'autres muscles, comme par exemple le muscle du mollet, reflète plutôt le niveau général de tension (Hazlett et al, 1994 ;McLeod et al, 1988).…”

Section: Psychophysiologie De L'anxiétéunclassified

Comment s’expriment physiologiquement l’hypervigilance et l’hyperréactivité décrites cliniquement pour l’anxiété ?

Zullino

Khazaal

Hättenschwiler

et al. 2004

smq

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Les sujets anxieux présentent souvent des troubles attentionnels avec un biais pour les stimuli à contenu menaçant. L’anxiété, comme toute autre émotion, s’accompagne de réactions physiologiques périphériques plus ou moins manifestes affectant le comportement et l’état de l’organisme. Compte tenu des modifications psychophysiologiques associées à l’anxiété et aux troubles anxieux on s’est intéressé à rechercher des liens entre les mesures psychophysiologiques et les phénomènes de sélectivité attentionnelle. Ce phénomène a effectivement été observé, c’est-à-dire une activation élective de fonctions psychophysiologiques comme réaction à des stimuli menaçants, et une diminution lors de l’exposition aux stimuli neutres.Anxious people often show a particular attentional focus towards potentially threatening stimuli. Like any other emotion, anxiety goes along with physiological reactions, which may be more or less noticeable, and may impair behavior and physical wellness. In view of the psychophysiological reactions related with anxiety and anxiety disorders, it seems important to examine potential correlations between psychophysiological activity and the phenomena of hypervigilance. In fact, selective psychophysiological activation has repeatedly been found as a reaction to pathology-specific threatening stimuli in patients with anxiety disorders, whereas their psychophysiological responses appeared often to be blunted when they were submitted to neutral stimuli.Los pacientes ansiosos presentan con frecuencia trastornos de atención con una inclinación a los estímulos de contenido amenazador. La ansiedad, como cualquier otra emoción, se acompaña de reacciones fisiológicas periféricas, más o menos manifiestas, que afectan el comportamiento y el estado del organismo. Dadas las modificaciones psicofisiológicas asociadas con la ansiedad y los trastornos de ansiedad, nos interesamos en la investigación de las relaciones entre las medidas psicofisiológicas y los fenómenos de selectividad de la atención. Este fenómeno ha sido efectivamente observado, es decir existe una activación electiva de las funciones psicofisiológicas como reacción a los estímulos amenazadores y una disminución en el momento de la exposición a los estímulos neutros.As pessoas ansiosas apresentam freqüentemente transtornos da atenção com uma tendência para os estímulos de conteúdo ameaçador. A ansiedade, como qualquer outra emoção, é acompanhada de reações psicológicas periféricas mais ou menos manifestas que afetam o comportamento e o estado do organismo. Levando em consideração as modificações psicofisiológicas associadas à ansiedade e aos transtornos de ansiedade, ficamos interessados em pesquisar os elos entre as medidas psicofisiológicas e os fenômenos de seletividade da atenção. Este fenômeno foi realmente observado; trata-se de uma ativação eletiva de funções psicofisiológicas em reação a estímulos ameaçadores e uma diminuição durante a exposição a estímulos neutros

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“…However, data are limited in animals. These studies were conducted to define the anxiolytic activities of some drugs, and to measure anxiety, fear response, stress, and arousal [11,12].…”

Section: Introductionmentioning

confidence: 99%

Investigation of dose related effects of propolis on anxiety and some biochemical parameters with sympathetic skin response and increased T-maze

Nisari¹,

Emre²,

Dolu³

et al. 2020

Journal of Surgery and Medicine

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Skin conductance reaction (SCR)-habituation test, an elementary model of anxiety as a tool to assess anxiogenic activities of some drugs

Cited by 9 publications

References 7 publications

Venlafaxine Versus Applied Relaxation for Generalized Anxiety Disorder: A Randomized Controlled Study on Clinical and Electrophysiological Outcomes

Venlafaxine Versus Applied Relaxation for Generalized Anxiety Disorder: A Randomized Controlled Study on Clinical and Electrophysiological Outcomes

Comment s’expriment physiologiquement l’hypervigilance et l’hyperréactivité décrites cliniquement pour l’anxiété ?

Investigation of dose related effects of propolis on anxiety and some biochemical parameters with sympathetic skin response and increased T-maze

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