Skin Care Formulations and Lipid Carriers as Skin Moisturizing Agents

Pavlou, Panagoula; Siamidi, Angeliki; Varvaresou, Athanasia; Vlachou, Marilena

doi:10.3390/cosmetics8030089

Cited by 19 publications

(15 citation statements)

References 42 publications

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“…Nanonośniki, ze względu na swoje rozmiary, są w stanie przeniknąć przez warstwę rogową naskórka bez degradacji komórek i dotrzeć do głębszych warstw skóry oraz tkanek podskórnych [49], umożliwiając dotarcie składnika aktywnego do miejsca docelowego [3,4,[50][51][52][53]. Biorąc pod uwagę powyższe aspekty, liposomy stają się wręcz idealnymi nanonośnikami, ponieważ nie tylko zapewniają wszelkie korzyści związane z nanotechnologią, ale również umożliwiają celowanie w konkretne komórki.…”

Section: Transport Substancji Antyoksydacyjnychunclassified

PEGylated (modified with polyethylene glycol) liposomes – their structures and properties

Pieczara¹,

Starosta²

2023

Aesth Cosmetol Med

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Liposomes are nanocarriers consisting of a phospholipid bilayer, similar in composition and structure to a cell membrane. Such a feature provides several possibilities related to the transport and delivery of biologically active substances to the specific cells in organisms. It is now becoming more and more popular to modify lipid carrier shells to achieve higher specificity and efficiency of transport into cells, and to reduce immunogenicity. The article aimed to present the properties, characteristics and application of liposomes modified with polyethylene glycol (PEG). The most common modification is a coating of liposomes with PEG, then sterically stabilized PEGylated vesicles are formed. PEGylation is currently a pillar of liposomal technologies due to the high efficiency of this type of nanocarrier and the possibility of attaching ligands to polymer chains. This article presents the characteristics of liposomes as carriers of substances, their structures, and types of cell interactions with a special emphasis on PEGylated liposomes.

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Section: Transport Substancji Antyoksydacyjnychunclassified

PEGylated (modified with polyethylene glycol) liposomes – their structures and properties

Pieczara¹,

Starosta²

2023

Aesth Cosmetol Med

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“…Therefore, research and innovation are based on special bioactive pharmaceutical/cosmetic-emulsions and/or smart cosmeceutical-tissues capable, for example, to continually release small doses of active ingredients through the skin' intercellular or intracellular pathways for obtaining protective/moisturizing or therapeutic effects [65][66][67][68][69][70][71]. Moreover, tissues and clothing may impair a further antimicrobial defense, providing mechanical barrier against insect bites, mosquito and protozoa as well as has to protect from fungi, bacteria and viruses responsible for infection and allergy problems [59,60].…”

Section: Biofunctional Textiles and Nanocomposites For Medical And Cosmetic Usementioning

confidence: 99%

Food Loss and Food Waste for Green Cosmetics and Medical Devices for a Cleaner Planet

et al. 2022

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To stay wealthy in a world where all can live in prosperity and wellbeing, it is necessary to develop sustainable growth at net zero emissions to stop climate change, neutralizing both risks and diseases such as the COVID-19 pandemic and inequalities. Changing the worldwide use of the great quantity of food loss and waste can help to move in this direction. At this purpose, it seems useful to transform food waste into richness, extracting and using its content in natural ingredients and biopolymers to make new sustainable products and goods, including cosmetics and medical devices. Many of these ingredients are not only bioactive molecules considered of interest to produce these consumer products but are also useful in reducing the environmental footprint. The active agents may be obtained, for example, from waste material such as grapes or olive pomace, which include, among others natural polymers, phythosterols, vitamins, minerals and unsaturated fatty acids. Among the polymers, chitin and lignin have shown particular interest because biodegradable, nontoxic, skin- and environmentally friendly ingredients can be obtained at low cost from food and forestry waste, respectively. According to our experience, these polymers may be used to make nanocomposites and micro-nanoparticles that encapsulate different active ingredients, and which may be embedded into gel and non-woven tissues to realize advanced medications and smart cosmeceuticals. However, to utilize food waste in the best possible way, a better education of both industry and the consumer is considered necessary, introducing all to change the ways of production and living. The consumer has to understand the need to privilege, food, cosmetics and goods by selecting products known to be effective that also have a low release of carbon dioxide. Thus, they must pay heed to purchasing cosmetics and medical devices made by natural ingredients and packaged by biodegradable and/or reusable containers that are possibly plastic free. Conversely, the industry must try to use natural raw materials obtained from waste by changing their actual production methods. Therefore, both industry and the consumer should depart from the linear economy, which is based on taking, making, and producing waste, to move into a circular economy, which is based on redesigning, reducing, reusing and recycling. Some examples will report on the possibility to use natural polymers, including chitin and lignin, to produce new cosmeceutical tissues. These innovative tissues, to be used as biodegradable carriers for making smart cosmetics and medical devices, may be produced at zero waste to save our health and the planet biodiversity.

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“…One such question pertains to the appropriate concentration of AHAs to achieve the desired therapeutic effects while minimizing the risk of adverse reactions, such as skin irritation and sensitivity [3]. Additionally, the pH of AHA formulations has been a subject of inquiry, as it can influence the stability and efficacy of these compounds [5]. Achieving the ideal balance between efficacy and tolerability requires a meticulous understanding of these factors.…”

Section: Introductionmentioning

confidence: 99%

Topical AHA in Dermatology: Formulations, Mechanisms of Action, Efficacy, and Future Perspectives

Karwal,

Mukovozov

2023

Cosmetics

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The utilization of topical formulations containing alpha hydroxy acids (AHAs) has garnered considerable attention. This review summarizes the effectiveness of the most common topical AHA formulations, including mechanisms of action and future research directions. AHAs have a dramatic impact on diverse skin conditions, enhancing texture and stimulating collagen synthesis. Uncertainties persist regarding optimal concentration, pH, and vehicle for maximum efficacy. Advancements in formulation technologies offer opportunities for AHA penetration and stability. Understanding mechanisms is vital for skincare optimization. The review covers AHAs, their concentrations, formulation considerations, safety measures, and future directions.

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Skin Care Formulations and Lipid Carriers as Skin Moisturizing Agents

Cited by 19 publications

References 42 publications

PEGylated (modified with polyethylene glycol) liposomes – their structures and properties

PEGylated (modified with polyethylene glycol) liposomes – their structures and properties

Food Loss and Food Waste for Green Cosmetics and Medical Devices for a Cleaner Planet

Topical AHA in Dermatology: Formulations, Mechanisms of Action, Efficacy, and Future Perspectives

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