Skin Cancer Management 2009
DOI: 10.1007/978-0-387-88495-0_16
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Skin Cancer in Skin of Color

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Cited by 6 publications
(3 citation statements)
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“…The greater melanin in the epidermis, which screens twofold as much UV light as that in Caucasians' epidermis, is principally responsible for the lower incidence of skin malignancies in darker-skinned races. Darker-skinned populations have large and more melanized melanosomes which absorb and disperse energy higher efficiently than Caucasians' smaller, melanosomes [ 82 ]. Skin cancer in non-White people frequently manifests at a later stage, which makes the prognosis poorer than in White individuals.…”
Section: Mechanism Of Skin Cancer Progressionmentioning
confidence: 99%
“…The greater melanin in the epidermis, which screens twofold as much UV light as that in Caucasians' epidermis, is principally responsible for the lower incidence of skin malignancies in darker-skinned races. Darker-skinned populations have large and more melanized melanosomes which absorb and disperse energy higher efficiently than Caucasians' smaller, melanosomes [ 82 ]. Skin cancer in non-White people frequently manifests at a later stage, which makes the prognosis poorer than in White individuals.…”
Section: Mechanism Of Skin Cancer Progressionmentioning
confidence: 99%
“…Although melanin is a major protective physiological barrier in skin damage due to UV radiation, it does not prevent skin cancer (Halder & Bridgeman-Shah, 1995). Research shows that every skin type, regardless of pigment, is susceptible to skin cancer (Beech, Harb, & Reed, 2004;Jackson, 2010). Even in people with darker skin, like African Americans, recent exposure to the sun increases epidermal melanin, which indicates UV damage to the skin (CDC, 2010a).…”
Section: Skin Cancer and African Americans -Health Disparitiesmentioning
confidence: 99%
“…8 While melanin’s UVR shielding effect undoubtedly accounts for some of the difference of the lifetime melanoma risk, highly pigmented skin provides a sun protective factor (SPF) of only 2-3 versus lightly pigmented skin, which seems insufficient to completely explain the large difference in skin cancer incidence between people with lightly pigmented vs darkly pigmented skin. 9,10 Furthermore, a UVR shielding effect does not fully explain decades of epidemiologic data suggesting that there are UV-independent determinants of melanoma risk that also correlate with skin pigment type. Melanomas arising in completely sun-protected areas, such as anorectal melanoma, are 13-fold higher in people with lightly pigmented skin than those with darkly pigmented skin.…”
Section: Introductionmentioning
confidence: 99%