Skin banking in the UK: the need for proper organization

Freedlander, E.; Boyce, S.; Ghosh, M.M.; Ralston, David R.; MacNeil, Sheila

doi:10.1016/s0305-4179(97)00093-4

Cited by 8 publications

(9 citation statements)

References 16 publications

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“…The interest in the production of fresh and long‐term stored viable skin grafts has been increasing continuously [148]. Experience leads to the suggestion that there is a clinical need for human cadaver allograft skin (HCAS) to be used both for research purposes and as a means of providing immediate coverage of excised burn wounds as a temporary biologic dressing when limited available skin donor sites or the overall patient condition do not permit immediate grafting with autologous skin [147, 149, 150]. On the other hand, HCAS can also be used as a dressing to cover widely meshed autografts in large burns [151].…”

Section: Burn Wound Excision and Reconstructionmentioning

confidence: 99%

State of the Art in Burn Treatment

Gunn²,

2005

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Optimal treatment of burn victims requires deep understanding of the profound pathophysiological changes occurring locally and systemically after injury. Accurate estimation of burn size and depth, as well as early resuscitation, is essential. Good burn care includes also cleansing, debridement, and prevention of sepsis. Wound healing, is of major importance to the survival and clinical outcome of burn patients. An ideal therapy would not only promote rapid healing but would also act as an antiscarring therapy. The present article is a literature review of the most up-to-date modalities applied to burn treatment without overlooking the numerous controversies that still persist.

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Section: Burn Wound Excision and Reconstructionmentioning

confidence: 99%

State of the Art in Burn Treatment

Gunn²,

2005

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“…In 1996, it cohosted the First World Conference in Tissue Banking with the Asia Pacific Association of Surgical Tissue Banking (APASTB) [ 39 ]. The British Association of Tissue Banking and the Spanish Association of Tissue Banks (Asociación Española de Bancos de Tejidos) were also set up to meet the needs of their respective countries [ 41 ], in addition to the prevailing legislations, such as the United Kingdom Human Tissue Authority’s regulations [ 42 ] and the Spanish Decree [ 43 ].…”

Section: Reviewmentioning

confidence: 99%

A Review of Skin Banking Guidelines and Standards Worldwide: Towards the Harmonization of Guidelines for Skin Banking in Therapeutic Applications for the Regions under the Asia Pacific Burn Association (APBA)

et al. 2020

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Currently, there are no harmonized guidelines which govern skin banking in the Asia Pacific region. Therefore, skin banks are either unregulated or rely on their nation’s legislation or international accreditation to uphold their quality standards. A new set of skin banking guidelines was developed through a comprehensive review and collation of best international practices for the Asia Pacific Burn Association (APBA) members, from donor screening and testing, to skin recovery, processing, storage and distribution, and quality assurance. National regulatory requirements reviewed include the European directives, Australia’s Therapeutic Goods Administration and Singapore’s tissue banking standards. Further technical and quality management recommendations are referenced from the American Association of Tissue Banks (AATB), the United States Food and Drug Administration standards and guidance documents, various relevant European guides, Japanese Society of Tissue Transplantation guidelines and the Asia Pacific Association of Surgical Tissue Banking. Adapted mainly from the AATB standards, the new Asia Pacific Burn Association Guidelines for Skin Banking in Therapeutic Applications offer a comprehensive manual, addressing: governance and contracts; staff responsibilities; quality management; facilities, equipment and supplies management; donor consent and testing; and recommendations of good practices pertaining to skin recovery, processing, storage and distribution. Besides complementing current generic regulations, they provide technical specifications of major aspects unaddressed in most legislations. This inaugural set of new regional skin banking guidelines would be a start for regional members of the APBA to adopt, and will hopefully culminate in a set of standards so that, in the long run, skin allografts from this region can be of similar quality, which can simplify import process and facilitate the exchange of allografts between members.

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“…5,6 Cryopreservation is defined as a process in which the biological and structural functions of tissues or cells are preserved by cooling to subzero temperatures in a cryoprotectant such as dimethyl sulfoxide or glycerol (Table 3). Cryopreservation of skin allografts requires rapid processing phases at low temperature to maintain sufficient cell viability.…”

Section: Cryopreservation and Freezingmentioning

confidence: 99%

“…6 Donor skin procurement, processing and banking were introduced in Italy in the mid-1990s to meet the growing demand for transplant tissue. 7 The first laboratories were created as centers for the treatment of severe burns; they were later organized into more complex structures (tissue establishments), including skin banks.…”

mentioning

confidence: 99%

Current insights into skin banking: storage, preservation and clinical importance of skin allografts

Tognetti¹,

Pianigiani²,

Ierardi³

et al. 2017

BSAM

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Donor skin and dermal grafts are used in several types of loss of substance for different clinical purposes. As biological physiological medication, donor skin grafts can promote re-epithelization, shorten healing time, alleviate pain and protect dermal and subcutaneous structures such as cartilage, tendons, bones and nerves. Though a great variety of dermal matrices and skin equivalents, both synthetic and semisynthetic, are now available for wound treatment, viable human skin allografts remain an important therapeutic choice for extensive deep burns and hard-to-heal wounds. In such cases, viable skin allografts have significantly better clinical outcomes than unviable human-derived allografts or synthetic medications. The demand for human-derived skin bioproducts continues to be a reason for the existence of skin banks. Skin bank organization is complex and requires continuous updating. Careful donor selection, thorough microbiological and serological donor screening for transmissible diseases and rigorous quality control during tissue preparation are necessary to minimize the risk of transmission of pathogenic agents. Skin banks must also observe standardized reproducible procedures to ensure tissue traceability and biological safety in all phases of processing and to avoid new biological contamination. Constant training and periodic checks are needed to keep skin bank operators attentive and responsible. Finally, skin banks should guarantee collection and storage of highly viable skin. Here, we discuss available tissue storage methods and the different types of skin bioproducts.

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Skin banking in the UK: the need for proper organization

Cited by 8 publications

References 16 publications

State of the Art in Burn Treatment

State of the Art in Burn Treatment

A Review of Skin Banking Guidelines and Standards Worldwide: Towards the Harmonization of Guidelines for Skin Banking in Therapeutic Applications for the Regions under the Asia Pacific Burn Association (APBA)

Current insights into skin banking: storage, preservation and clinical importance of skin allografts

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