Skin and soft tissue infections in the transplant population

Abstract

Solid organ and hematopoietic stem cell transplant recipients are more likely to develop skin and soft tissue infections, which may be caused by common or atypical pathogens. Skin and soft tissue anatomic abnormalities may act as portals of entry for infection, and may result from surgery, venous access, immunosuppressive medications, and other etiologies. Systemic infection may sometimes be recognized by investigation of skin manifestations. Many noninfectious processes of the skin and soft tissues can mimic infection, complicating the diagnosis. Prompt dermatologic consultation and skin biopsy are essential in this vulnerable population. Treatment of infection in transplant recipients may necessitate reduction of immunosuppression, in addition to other adjunctive therapies. Interesting and important new findings about skin and soft tissue infections in transplant recipients are the focus of this review.

Hautinfektionen nach Transplantation

“…Folgende spezielle Aspekte können für organtransplantierte Patienten mit Hautinfektionen herausgestellt werden: F Im Vordergrund stehen bakterielle, mykotische und virale Hautinfektionen, die den ersten Hinweis für eine systemische Manifestation geben können [4,6,7,12,13]. F Die Häufigkeit dieser Infektionen ist sehr hoch, wobei 55-97% organtransplantierter Patienten betroffen sind [13].…”