Skin and Skin Disease Throughout Life

Gianfaldoni, Serena; Tchernev, Georgi; Tirant, Michael; Wollina, Uwe; Castillo, David; França, Katlein; Lotti, Torello

doi:10.1007/978-3-319-53811-2_15

Cited by 3 publications

(4 citation statements)

References 72 publications

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“…152,154 Older persons are more prone to acquiring skin diseases such as pruritus, dermatitis and infections due to declining immune function and agerelated changes in the integrity and barrier of their skin that result in fragile skin. 153,155 Exposing the skin to an irritant repeatedly can lead to a vicious cycle of partial restoration, increased inflammation and damage. Long-term contact with these irritants can cause harm to fragile and aging skin, which has poorer baseline function and recovery time after an acute injury.…”

Section: Diaper Candidiasismentioning

confidence: 99%

“…As incontinent individuals may have to wear disposable diapers or underpads, the occlusive nature of these products contributes to the moist and warm environments in the diaper region, which are further exacerbated by irritants such as urine, stool or loose, watery stool 152,154 . Older persons are more prone to acquiring skin diseases such as pruritus, dermatitis and infections due to declining immune function and age‐related changes in the integrity and barrier of their skin that result in fragile skin 153,155 . Exposing the skin to an irritant repeatedly can lead to a vicious cycle of partial restoration, increased inflammation and damage.…”

Section: Cutaneous Candidiasis Caused By Candida Sppmentioning

confidence: 99%

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Candida albicans skin infection in diabetic patients: An updated review of pathogenesis and management

Shahabudin,

Azmi,

Lani

et al. 2024

Mycoses

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Candida species, commensal residents of human skin, are recognized as the cause of cutaneous candidiasis across various body surfaces. Individuals with weakened immune systems, particularly those with immunosuppressive conditions, are significantly more susceptible to this infection. Diabetes mellitus, a major metabolic disorder, has emerged as a critical factor inducing immunosuppression, thereby facilitating Candida colonization and subsequent skin infections. This comprehensive review examines the prevalence of different types of Candida albicans‐induced cutaneous candidiasis in diabetic patients. It explores the underlying mechanisms of pathogenicity and offers insights into recommended preventive measures and treatment strategies. Diabetes notably increases vulnerability to oral and oesophageal candidiasis. Additionally, it can precipitate vulvovaginal candidiasis in females, Candida balanitis in males, and diaper candidiasis in young children with diabetes. Diabetic individuals may also experience candidal infections on their nails, hands and feet. Notably, diabetes appears to be a risk factor for intertrigo syndrome in obese individuals and periodontal disorders in denture wearers. In conclusion, the intricate relationship between diabetes and cutaneous candidiasis necessitates a comprehensive understanding to strategize effective management planning. Further investigation and interdisciplinary collaborative efforts are crucial to address this multifaceted challenge and uncover novel approaches for the treatment, management and prevention of both health conditions, including the development of safer and more effective antifungal agents.

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Section: Diaper Candidiasismentioning

confidence: 99%

Section: Cutaneous Candidiasis Caused By Candida Sppmentioning

confidence: 99%

Candida albicans skin infection in diabetic patients: An updated review of pathogenesis and management

Shahabudin,

Azmi,

Lani

et al. 2024

Mycoses

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“…156 In 2009, Choi and Yoo prepared wound-adhesive and thermo-responsive hydrogels loaded with recombinant human epidermal growth factor (rhEGF) and these showed release rates that were dependent on degradation rates of the hydrogels. 157 Covalent crosslinked alginate gels are currently playing a role in wound dressing as they have an ability to absorb the wound excaudate in both gel and freeze-dried form and provide a physiologically moist environment while prohibiting the bacterial infection growth. 158 Polymers such as Chitosan 159 and alginate 160 have proven to be vital when it comes to wound dressing as individuals and as a combination.…”

Section: Potential Of Nanogels In Different Diseasesmentioning

confidence: 99%

Review on nanogels and their applications on dermal therapy

Botha,

Mushonga,

Onani

2023

Polymers and Polymer Composites

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A nanogel is a cross-linked nano-sized, a three-dimensional network of hydrophilic polymers with an ability to swell by holding large amount of water while maintaining the structure due to chemical or physical cross-linking of individual polymer chains. Nanogels can be made up of synthetic and/or natural polymers resulting in a cationic, anionic, or neutral system depending on the bound groups’ charges. Currently, these materials are receiving tremendous attention in research due to their properties. They are extensively investigated as carriers in the biomedical field. At present, there is an expansion of research into dermatologic treatment due to a critical need for new treatment options to treat skin diseases. The skin itself provides a natural barrier against particle penetration for topical delivery. However, it also offers a potential approach for the delivery of therapeutics, especially in diseased skin via the openings of hair follicles. Recent innovation might be achieved in the field of dermatological treatment with improvement in the dermal localization of bio-actives into the affected skin region. This report looks at what has been done in the investigation of nanogels as drug carriers for topical therapy.

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“…There are a number of symptoms that may appear on the skin affected by inflammation, which differ in severity, depending on the cause of this problem. In general, some symptoms of dermatitis can be summarized as follows: [13] • Itching • The appearance of painful sores on the skin • Suffering from redness and swelling • a change in skin color • Skin wrinkling and peeling • The appearance of blisters…”

Section: Introductionmentioning

confidence: 99%

Detection and diagnosis of skin diseases by using snake algorithm and neural networks

Ramo¹

2022

Technium

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This research presents a medical application to diagnose types of skin diseases based on the axis of dermatology, where a computer intelligent system was built based on identifying and diagnosing the type of skin inflammation, and this system called (SANN) (Snake Algorithm Neural Network). The system consists of two stages, the first stage is the axis of locating the presence of skin inflammation and distinguish it from uninfected skin by performing the initial processing of the image using the snake algorithm. while the second stage using neural networks to diagnose types of skin disease that were identified in the first stage by adding some improvements to the neural networks to work more efficiently for diagnosis. The suggested SANN system was applied to 250 images, and the accuracy and execution time were calculated. The results showed that using the system based on the snake algorithm and neural networks in the process of identifying and diagnosing types of dermatitis (psoriasis or Spider birthmark) achieves high performance and accuracy, and gave a diagnosis rate of 88.9%

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Skin and Skin Disease Throughout Life

Cited by 3 publications

References 72 publications

Candida albicans skin infection in diabetic patients: An updated review of pathogenesis and management

Candida albicans skin infection in diabetic patients: An updated review of pathogenesis and management

Review on nanogels and their applications on dermal therapy

Detection and diagnosis of skin diseases by using snake algorithm and neural networks

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