Skin Adnexal Tumors: A study of 26 cases

Abstract

Background: Skin adnexal tumours are a category of rare tumours. They usually present as painless nodules and papules. The diagnosis of these tumours poses a challenge, because there is usually a discrepancy in clinical and histopathological diagnosis.
 Aims: To study the skin biopsies received in our department and compare their clinical and histopathological diagnosis.
 Material and methods: Prospective study of skin biopsies received in our department over a period of 1 year. The biopsies were processed and stained with haematoxylin and eosin and studied under the light microscope.
 Results: Out of the 26 cases studied, 25 were found to be benign tumours with a single case of keratoacanthoma. The most common tumour encountered was pilomatricoma and the least common was syringoma. Only four cases showed clinical correlation with histopathological diagnosis.
 Conclusion: It can be therefore concluded that skin adnexal tumours are rare tumours which need histopathological examination for their accurate diagnosis.

Five‐year pattern of adnexal tumors of the skin in Ethiopia

“…16 The most frequent line of differentiation in our study was sweat gland (48.6%), followed by follicular (33.6%) and sebaceous (16.4%). This finding is similar to many of the previous studies done in the United Kingdom, 11 Turkey, 25 India, 7,11,[28][29][30] Nigeria, 9,20,23 and Egypt. 16 However, a study in India by Kala et al and Sinha et al, 18,27 a study in Nepal, 19 a study in Burkina Faso, 31 Morocco, 21 and a study in Slovakia 1 found hair follicle tumors to be the most common.…”

“…31 Many other studies also reported similar findings with predominance of benign tumors, but all the rest were >90%. 7,12,16,17,21,26,27 The most common location for the tumors in our study was the scalp (25.3%), followed by the face (20.5%), and then the lower extremity (14.4%). Therefore, the head and neck region (48.6%) was the most common body site to be involved overall.…”

“…This finding corresponds to most other studies. Studies in India by Kala et al 18 and Viswanathan et al 7 found the 3rd decade as the most common age group. A study in Pakistan reported the most common age to be 26-50 years.…”

“…6 Adnexal tumors of the skin are usually misdiagnosed clinically as they often present with nonspecific flesh-colored single or multiple papulonodular lesions with varying clinicopathologic significance according to the type and clinical context. [7][8][9] Histopathology can provide us with diagnostic confirmation. However, even with histopathology, the diagnosis of skin adnexal tumors presents difficulties as a result of the large variety of tumors and their variant forms, the frequency of differentiation along multiple lines in the same tumor, and also the various classification schemes, complicated nomenclature, and their relative rarity, which make the physicians less familiar.…”

Syringocystadenoma papilliferum in a 20-year-old adult: a case report and literature review

“…Study from Lee et al . showed that syringocystadenoma papilliferum are most often located at head and neck area [ 2 , 3 ]. Other sites include arms, face, chest, abdomen, arms, thighs and perineum [ 4 ].…”