Skeletal Scintigraphy in the Multimodality Assessment of Young Children With Acute Skeletal Symptoms

Connolly, Leonard P.; Connolly, Susan A.

doi:10.1097/01.rlu.0000082663.54359.d9

Cited by 29 publications

(8 citation statements)

References 47 publications

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“…In mammals with septic synovitis or osteomyelitis, cultures of blood, synovial fluid, synovial membrane, and bone are often negative, and diagnosis is based on a combination of supportive clinical, laboratory, and imaging findings 42–47 . In two turtles, bacteria were isolated from the affected bone or joint, while blood cultures were negative in six turtles.…”

Section: Discussionmentioning

confidence: 99%

Scintigraphic and Radiographic Evaluation of Appendicular Skeletal Lesions in Cold‐stunned Kemp's Ridley Sea Turtles

Solano¹,

Innis²,

Smith³

et al. 2008

Vet Radiology Ultrasound

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Osteolytic appendicular skeletal lesions in eight-stranded, cold-stunned Kemp's ridley sea turtles (Lepidochelys kempii) were evaluated using radiography and skeletal scintigraphy. Radiographic studies were performed monthly in most animals. Follow-up scintigraphy was performed 45-120 days after the initial exams in six turtles. Radiographically, lesions slowly progressed from an early osteolytic process contained to either the proximal or distal end of long bones, to a later stage characterized by thickening of the affected bone, sclerosis, and remodeling of the lesion borders. In seven turtles, the initial scintigrams were characterized by at least one focus of abnormal radiopharmaceutical uptake that correlated with a lytic site noted in radiographs. In five turtles, scintigraphic lesions were characterized by asymmetric radiopharmaceutical uptake rather than by increased intensity of uptake. Scintigraphic studies obtained more than 4 months after the appearance of clinical and radiographic signs had minimal, if any, abnormal radiopharmaceutical uptake, despite the persistence of abnormal radiographic findings. Skeletal scintigraphy is an effective method for more precisely determining if and when these animals can be returned to the wild. Animals were released if normal radiopharmaceutical uptake was seen during initial examination, or if decreased uptake was noted between serial examinations. In four of the turtles, resolution of abnormal scintigraphic findings permitted an objective decision to discontinue antibiotic and antifungal therapy. Seven of the eight turtles were released after correlation of the clinical signs with the imaging findings. Radiographs, however, are still needed to facilitate the correct identification of lesions with scintigraphy.

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Section: Discussionmentioning

confidence: 99%

Scintigraphic and Radiographic Evaluation of Appendicular Skeletal Lesions in Cold‐stunned Kemp's Ridley Sea Turtles

Solano¹,

Innis²,

Smith³

et al. 2008

Vet Radiology Ultrasound

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show abstract

“…Some experts prefer bone scan as the initial study in the evaluation of suspected uncomplicated osteomyelitis of the long bones. It is less expensive than MR imaging, sedation of the child is generally not necessary, and it is particularly useful when multifocal osteomyelitis is suspected or the exact location of infection is not obvious on physical examination [16,17]. Radionuclide scans may be positive in other illnesses that result in increased osteoblastic activity, including malignancy, trauma, cellulitis, postsurgery, and arthritis.…”

Section: Diagnosismentioning

confidence: 99%

Bone and Joint Infections in Children

Gutierrez

2005

Pediatric Clinics of North America

218

210

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“…Bone scintigraphy can confirm the diagnosis 24-48 hours after onset of symptoms even in the presence of low mineralization of the bone. Some authors prefer scintigraphy rather than magnetic res-onance imaging (MRI) because the procedure is less expensive, generally does not require sedation and is useful to diagnose multifocal types or in cases when the exact localization of the infection is not obvious on physical examination [17]. Bone scintigraphy can be positive in diseases with increased osteoblastic activity such as tumors, fractures, cellulites and arthritis [15,17].…”

Section: Diagnosismentioning

confidence: 99%

“…However, ultrasonography does not differentiate between infectious and non-infectious joint fluid. Bone scintigraphy is useful when there is suspicion of osteomyelitis [17].…”

Section: Diagnosismentioning

confidence: 99%

Acute bone and joint infections in children and therapeutic options

Caramia¹,

Ruffini²,

Zaffanello

et al. 2015

J Pediatr Infect Dis

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Osteomyelitis and septic arthritis show similar problems in diagnosis and treatment. The majority of bone or joint infections are caused by spread of the bacteria through the bloodstream or occasionally by entry of organisms through an open wound, by puncture or by extension of infection from adjacent tissue. The most common causative organism is Staphylococcus aureus but many other organisms may be responsible for a bone or joint infections. Successful treatment of osteomyelitis and septic arthritis in infancy and childhood depends on early recognition and prompt institution of therapy. Inappropriate or delayed treatment may result in chronic osteomyelitis or irreversible joint destruction. This article reviews current information regarding pathogenesis, epidemiology and microbiology of pediatric osteomyelitis and septic arthritis and the clinical presentation, diagnosis and treatment of these infections.

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Skeletal Scintigraphy in the Multimodality Assessment of Young Children With Acute Skeletal Symptoms

Cited by 29 publications

References 47 publications

Scintigraphic and Radiographic Evaluation of Appendicular Skeletal Lesions in Cold‐stunned Kemp's Ridley Sea Turtles

Scintigraphic and Radiographic Evaluation of Appendicular Skeletal Lesions in Cold‐stunned Kemp's Ridley Sea Turtles

Bone and Joint Infections in Children

Acute bone and joint infections in children and therapeutic options

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