Skeletal muscle mass of old Japanese women suffering from walking difficulty in nursing home

Abstract

By using 24 hour urinary creatinine levels, skeletal muscle mass (kg), its rate (%) of body weight and creatinine height index (%) were determined in old Japanese women suffering from walking difficulty in nursing home and compare with those of young university students. Those of old subjects showed approximately 30-50%, 36-44% and 44-46% of young subjects, respectively. It is suggested that these values are important and useful biomarkers for the planning and the achievement of rehabilitation program for the maintaining and restoring skeletal muscle mass and for the careful support by registered care workers to aged persons. J. Med. Invest. 65:122-125, February, 2018.

Effects of daily 1,000-IU vitamin D-fortified milk intake on skeletal muscle mass, power, physical function and nutrition status in Japanese

“…Muscle function decreases through the progression of sarcopenia, linking vitamin D and different symptoms (26)(27)(28)(29) because vitamin D receptor expression decreases with age (30,31). In our previous study, an age-related decrease in skeletal muscle mass and its cut-off levels for walking difficulty were clarified using 24-hour creatinine excretion as a measure of total-body skeletal muscle mass in a Japanese population including nursing home residents (4,5). The skeletal muscle function, skeletal muscle mass (kg, kg / m 2 , %BW) and CHI were also closely related to serum 25(OH)D levels (6).…”

“…It is characterized by the gradual age-related loss of muscle mass, muscle strength and physical performance, which leads to reduced mobility and an increased risk of falls, and is associated with premature death (1)(2)(3). In our previous studies, an age-related decrease in total-body skeletal muscle mass based on 24-hour creatinine excretion and age-related loss of muscle power and function were observed in a Japanese population including nursing home residents (4)(5)(6). Furthermore, a low vitamin D level is positively associated with reduced skeletal muscle mass, muscle function and strength.…”

Cut-off values for skeletal muscle strength and physical functions in Japanese elderly with walking difficulty

“…Understanding skeletal muscle function and muscle mass is important to provide sufficient rehabilitation and proper care in nursing homes. In our previous study, age-related decreases in skeletal muscle mass and cut-off levels for walking difficulty were calculated using 24-h creatinine excretion as a measure of total-body skeletal muscle mass in the Japanese population, including nursing home residents (10,11). Furthermore, the serum 25-hydroxyvitamin D [25(OH) D] level was closely related to skeletal muscle mass.…”