Skeletal muscle atrophy in clinical and preclinical models of chronic kidney disease: A systematic review and meta‐analysis
Ashley D. Troutman,
Eliott Arroyo,
Elizabeth M. Sheridan
et al.
Abstract:Patients with chronic kidney disease (CKD) are often regarded as experiencing wasting of muscle mass and declining muscle strength and function, collectively termed sarcopenia. The extent of skeletal muscle wasting in clinical and preclinical CKD populations is unclear. We evaluated skeletal muscle atrophy in preclinical and clinical models of CKD, with multiple sub‐analyses for muscle mass assessment methods, CKD severity, sex and across the different preclinical models of CKD. We performed a systematic liter… Show more
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