“…Twenty-one studies 3,4,6,8,9,15,[18][19][20][22][23][24][25][26][28][29][30][31][32][33][34] were retrospective, five studies 7,11,12,16,17 were prospective, and four studies 5,10,21,27 were prospective and randomized. Six studies 10,18,[22][23][24]33 compared the results with a control group of the same age, and eight studies 4,6,10,12,22,[32][33][34] analyzed the long-term effects of RME. Only two studies 10,17 specified that the subjects of the study groups were selected consecutively.…”