SKA3 targeted therapies in cancer precision surgery: bridging bench discoveries to clinical applications – review article
Dechao Feng,
Jie Wang,
Yuhan Xiao
et al.
Abstract:Spindle and kinetochore-associated complex subunit 3 (SKA3) is a microtubule-binding subcomplex of the outer kinetochore which plays a vital role in proper chromosomal segregation and cell division. Recently, SKA3 have been demonstrated its oncogenic role of tumorigenesis and development in cancers. In this review, we comprehensively deciphered SKA3 in human cancer from various aspects, including bibliometrics, pan-cancer analysis and narrative summary. We also provided top 10 predicted drugs targeting SKA3. W… Show more
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