Sjögren's syndrome – not just Sicca: renal involvement in Sjögren's syndrome

Abstract

The present case, as well as the limited number of reports in the literature, suggest that renal involvement, including IN, in pSS may improve with immunosuppressive therapy. Further studies are required to determine indications for and dosages of immunosuppressive treatment in patients with renal involvement of pSS.

A Case with Double Translocation and Sjögren’s Syndrome

“…9 Pseudohypoparathyroidism has also been previously described in patients with SS; this may explain the increased urinary calcium excretion and elevated parathyroid hormone levels in our patient. 10 Balanced reciprocal and Robertsonian translocations are the most common structural chromosomal abnormalities in human.…”

Distal Renal Tubular Acidosis and Diabetes Insipidus Leading to the Diagnosis Of Sjögren's Syndrome

“…The data available is scant, precluding an analysis of the relative benefits of each modality. 7 In our patient, corticosteroids without other adjunctive immunosuppresive agents was used, with an adequate response.…”

An 18-Year-Old Female with Weight Loss and Hypokalemia

“…However, 3%-9% of patients demonstrate clinically significant renal disease. 4 Although rare, presentation of severe renal disease may include hypokalemic paralysis, cardiac arrest, and renal failure. 4 The presence of distal RTA confers a significantly increased incidence of B-cell lymphoma in adults with SS.…”