Size control synthesis of melanin-like polydopamine nanoparticles by tuning radicals

Wang, Xianheng; Chen, Zhan; Yang, Peng; Hu, Junfei; Wang, Zhao; Li, Yiwen

doi:10.1039/c9py00517j

Cited by 82 publications

(59 citation statements)

References 42 publications

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“…Another effort to control the size of the PDA@NPs consists in adding either strong free radical scavengers (i.e edaravone) or stable free radicals (i.e PTIO) [50] during the synthesis, both resulting in a decrease in the NPs size (Fig 4). Inspired by the fact that eumelanin is always surrounded by a layer of proteins [40], a recent study has shown that the whole pool of proteins from the egg white allows to produce well controlled and stable eumelanin like material from DHI [52].…”

Section: How To Avoid Precipitation In Solution and To Produce Stablementioning

confidence: 99%

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Polydopamine as a stable and functional nanomaterial

Yakhlifi

Ball

2020

Colloids and Surfaces B: Biointerfaces

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The mussel inspired chemistry of dopamine leading to versatile coatings on the surface of all kinds of materials in a one pot process was considered as the unique aspect of catecholamine for a long time. Only recently, research has been undertaken to valorize the simultaneous oxidation and colloid formation in dopamine solutions in the presence of an oxidant. This mini review summarizes the synthesis methods allowing to get controlled nanomaterials, either nanoparticles, hollow capsules or nanotubes and even chiral nanomaterials from dopamine solutions. Finally the applications of those nanomaterials will be described.

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Section: How To Avoid Precipitation In Solution and To Produce Stablementioning

confidence: 99%

“…schematic illustration of the size controlled synthesis of PDA NPs by using radicalar species. Reproduced from ref [50]. with authorization.Yet, the problem of the precipitation is still not totally resolved.…”

mentioning

confidence: 99%

Polydopamine as a stable and functional nanomaterial

Yakhlifi

Ball

2020

Colloids and Surfaces B: Biointerfaces

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“…[ 356–360 ] Static light scattering (SLS) observes the average scattering intensity of a solution/suspension over a period of time, whereas dynamic light scattering (DLS) observes fluctuations of the scattered light over very short periods of time, offering insights into molecular weights of polymers and particle sizes (typically nanometer scale and upward). Light scattering has been used to study synthetic melanins (e.g., polydopamine [ 361,362 ] ), naturally occurring melanins in bacteria ( Vibrio natriegens [ 181 ] ), yeast ( Cryptococcus neoformans [ 167 ] ), fungi ( Aspergillus oryzae [ 363 ] ), mushrooms ( Inonotus hispidus [ 183 ] ), cuttlefish ( Sepia officinalis [ 362 ] ), and can be used to study the health of eyes for patients with various conditions (e.g., for patients with pigmentary dispersion glaucoma [ 364 ] ).…”

Section: Analysis Of Melaninsmentioning

confidence: 99%

Melanins as Sustainable Resources for Advanced Biotechnological Applications

et al. 2020

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Melanins are a class of biopolymers that are widespread in nature and have diverse origins, chemical compositions, and functions. Their chemical, electrical, optical, and paramagnetic properties offer opportunities for applications in materials science, particularly for medical and technical uses. This review focuses on the application of analytical techniques to study melanins in multidisciplinary contexts with a view to their use as sustainable resources for advanced biotechnological applications, and how these may facilitate the achievement of the United Nations Sustainable Development Goals.

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“…Melanin-like pDA nanoparticles have been synthesized with tunable sizes ranging from a few nanometers to hundreds of nanometers in aqueous solution at mildly basic pH values by the addition of different ratios of sodium hydroxide (NaOH) or ammonium hydroxide (NH 4 OH) to DA. During these processes, X. Wang reported that radicals could further control the growth of the particles by either quenching the radical intermediates of pDA or accelerating seed formation [12]. Particle size was also affected by buffers; N. F. D. Vecchia et al reported that the particle size of pDA increased with increasing initial DA concentration in phosphate or bicarbonate buffers, but inhibition of particle growth was observed in Tris buffer [13].…”

Section: Synthesis and Characterization Of Melanin-based Multifunctiomentioning

confidence: 99%

Recent advances in melanin-like nanomaterials in biomedical applications: a mini review

2019

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BackgroundMelanins are a group of biopigments in microorganisms that generate a wide range of colorants. Due to their multifunctionality, including ultraviolet protection, radical scavenging, and photothermal conversion, in addition to their intrinsic biocompatibility, natural melanins and synthetic melanin-like nanomaterials have been suggested as novel nano-bio platforms in biomedical applications.Main bodyRecent approaches in the synthesis of melanin-like nanomaterials and their biomedical applications have briefly been reviewed. Melanin-like nanomaterials have been suggested as endogenous chromophores for photoacoustic imaging and radical scavengers for the treatment of inflammatory diseases. The photothermal conversion ability of these materials under near-infrared irradiation allows hyperthermia-mediated cancer treatments, and their intrinsic fluorescence can be an indicator in biosensing applications. Furthermore, catechol-rich melanin and melanin-like nanomaterials possess a versatile affinity for various functional organic and inorganic additives, allowing the design of multifunctional hybrid nanomaterials that expand their range of applications in bioimaging, therapy, theranostics, and biosensing.ConclusionMelanin-like natural and synthetic nanomaterials have emerged; however, the under-elucidated chemical structures of these materials are still a major obstacle to the construction of novel nanomaterials through bottom-up approaches and tuning the material properties at the molecular level. Further advancements in melanin-based medical applications can be achieved with the incorporation of next-generation chemical and molecular analytical tools.

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Size control synthesis of melanin-like polydopamine nanoparticles by tuning radicals

Abstract: We report the first effort to control the size of polydopamine nanoparticles via adding either strong free radical scavengers (i.e. edaravone) or stable free radicals (i.e. PTIO˙) during the polymerization.

Cited by 82 publications

References 42 publications

Polydopamine as a stable and functional nanomaterial

Polydopamine as a stable and functional nanomaterial

Melanins as Sustainable Resources for Advanced Biotechnological Applications

Recent advances in melanin-like nanomaterials in biomedical applications: a mini review

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