Size and shape of the sella turcica in subjects withDown syndrome

Abstract

The sella turcica in DS differs in size and morphology when compared to individuals without the syndrome. The diameter and depth of the sella turcica in DS are larger than controls, with a tendency toward more abnormalities in the shape of sella turcica.

Sella turcica measurements on lateral cephalograms of patients with neurofibromatosis type 1

“…Area measurement values of this study in healthy individuals are similar to those of Israel [109] and Krennmair et al [69], but higher than those of Andredaki et al [29]. Mean value of sella entrance of the control group is between those published by Korayem and Alkofide [91] and Axelsson et al [108], but is higher than in a Greek population study [29]. Sella width is slightly larger in controls of this study compared to mean values of this item provided by Krennmair et al [69], Andredaki et al [29], but smaller than in the investigation of DiMario et al [36].…”

“…Indeed, a j-shaped sella is a well-documented, not infrequent finding on lateral cephalograms of healthy children and adolescents [87]. Therefore, this finding was regarded a radiological variant in this age group [78], [87], but association with certain pathologies was repeatedly emphasised, even recently [88], [89], [90], [91]. Indeed, the association of a j-shaped sella and OPG in NF1 is still a teaching content of textbooks of cranial radiology [68] and clinical reviews on OPG [92].…”

The age-dependent changes of sella turcica, frontal and sphenoid sinuses

“…Длина его у взрослых колеблется в пределах 10-13 мм, высота -8-9,5 мм. Переднезадний диаметр не выходит за пределы 5-16 мм, а глубина в норме от 4 до 12 мм [24][25][26][28][29][30][31][32][33][34][35][36][37]. В исследованиях D. Venieratos [27] длина ГЯ в пределах 10-14 мм, а ширина 7,5-12,5 мм.…”

“…M. Korayem и соавт. [32] определили, что у лиц в возрасте 12-22 лет с синдромом Дауна диаметр и глубина ТС боль-ше, чем в контрольной группе. Была установлена очевид-ная тенденция к аномальной морфологии ТС: искривлен-ная передняя стенка, перемычка, пирамидальная форма встречались чаще при синдроме Дауна, чем у лиц кон-трольной группы.…”

Clinical And Radiological Significance of Sella Turcica: A Literature Review

“…The morphological variations of sella turcica with greater severity are more commonly seen in syndromic patients such as Down's syndrome, William's syndrome, Seckel syndrome, and AxenfeldRieger syndrome [21][22][23][24]. An altered sella turcica morphology can be present in patients with spina bifida [25].…”