Sixth case of infective endocarditis caused by Gemella bergeri

Virgilio, Edoardo; Chieco, Paola Addario

doi:10.1016/j.bjid.2014.05.002

Cited by 9 publications

(20 citation statements)

References 3 publications

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“…have been reported in the literature [5,7,8,12,20] and among them only 8 were caused by G.bergeriae, including 7 adult cases and 1 pediatric case. [5][6][7]9,10,13] The majority of the patients described in the literature with G.bergeriae endocarditis had a good response to antibiotic therapy. [5][6][7]9,10,12,13] In 2014, Hussain et al [7] described the first fatal case of G.bergeriae infection, in which the patient with a history of rheumatic heart disease developed an embolic stroke as a complication of IE.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7]9,10,13] The majority of the patients described in the literature with G.bergeriae endocarditis had a good response to antibiotic therapy. [5][6][7]9,10,12,13] In 2014, Hussain et al [7] described the first fatal case of G.bergeriae infection, in which the patient with a history of rheumatic heart disease developed an embolic stroke as a complication of IE. Despite antibiotic therapy and intensive treatment, the patient expired due to intracerebral and subarachnoid hemorrhage secondary to rupture of a mycotic aneurysm in the right middle cerebral artery.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7][8] This report describes a fatal case of IE caused by G.bergeriae, which is part of the normal flora of the human oral cavity, slow growing fastidious bacteria, which can insidiously lead to a fulminant fatal outcome. [5][6][7][9][10][11][12][13][14] We present the second fatal case of IE caused by G.bergeriae.…”

Section: Introductionmentioning

confidence: 91%

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Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Ukudeeva¹,

Hawkins²,

Ahmad³

et al. 2017

Int J Biomed

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Ukudeeva¹,

Hawkins²,

Ahmad³

et al. 2017

Int J Biomed

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“…Logan et al [ 3 ] reported the first case of pediatric IE caused by G. bergeri in a boy with Tetralogy of Fallot and pulmonary atresia. Virgilio and Chieco [ 5 ] reported the sixth case of G. bergeri IE in an adult man with bicuspid aortic valve, using molecular diagnosis with 16S rRNA gene sequence analysis. Hussain et al [ 4 ] reported neurological complications of G. bergeri IE in a young patient with rheumatic heart disease that was complicated by embolic stroke and rupture of mycotic aneurysm with bad outcome.…”

Section: Discussionmentioning

confidence: 99%

“…Since then, only seven cases of G. bergeri endocarditis have been reported so far [ 1 – 4 ]. Predisposing cardiac abnormalities such as mitral valve prolapse, Tetralogy of Fallot, bicuspid aortic valve (BAV), and rheumatic heart disease seem to be the most important risk factors [ 2 – 5 ]. We describe herein a case of G. bergeri endocarditis of tricuspid valve with underlying tricuspid valve cleft.…”

Section: Introductionmentioning

confidence: 99%

First Case of Tricuspid Valve Endocarditis Caused byGemella bergeri

Pachirat

Watt

Pussadhamma

2015

Case Reports in Medicine

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Gemella bergeri is a Gram-positive cocci species arranged in pairs and composes the normal flora of oral cavity, digestive and urinary tract. Several species of Gemella are known to cause endocarditis. Here, we report the first case in Thailand of G. bergeri endocarditis whose blood culture was negative using routine methods but was positive by PCR identification of bacteria in the affected valve. A 37-year-old male presented with prolonged fever, weight loss, and dyspnea on exertion. By transthoracic echocardiography, he was suspected of having infective endocarditis of the tricuspid valve. The patient underwent tricuspid valve repair and vegetectomy. Routine hospital blood cultures were negative but G. bergeri was identified by PCR/sequencing of the heart valve tissue.

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Purpura fulminans with Lemierre’s syndrome caused by Gemella bergeri and Eikenella corrodens: a case report

et al. 2018

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BackgroundGemella bergeri is one of the nine species of the genus Gemella and is relatively difficult to identify. We herein describe the first case of septic shock due to a Gemella bergeri coinfection with Eikenella corrodens.Case presentationA 44-year-old Asian man with a medical history of IgG4-related ophthalmic disease who was prescribed corticosteroids (prednisolone) presented to our hospital with dyspnea. On arrival, he was in shock, and a purpuric eruption was noted on both legs. Contrast enhanced computed tomography showed fluid retention at the right maxillary sinus, left lung ground glass opacity, and bilateral lung irregular opacities without cavitation. Owing to suspected septic shock, fluid resuscitation and a high dose of vasopressors were started. In addition, meropenem, clindamycin, and vancomycin were administered. Repeat computed tomography confirmed left internal jugular and vertebral vein thrombosis. Following this, the patient was diagnosed with Lemierre’s syndrome. Furthermore, he went into shock again on day 6 of hospitalization. Additional soft tissue infections were suspected; therefore, bilateral below the knee amputations were performed for source control. Cultures of the exudates from skin lesions and histopathological samples did not identify any pathogens, and histopathological findings showed arterial thrombosis; therefore it was concluded that the second time shock was associated with purpura fulminans. Following this, his general status improved. He was transferred to another hospital for rehabilitation. The blood culture isolates were identified as Gemella bergeri and Eikenella corrodens. Gemella bergeri was identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry and confirmed by 16S rRNA gene sequencing later. The primary focus of the infection was thought to be in the right maxillary sinus, because the resolution of the fluid retention was confirmed by repeat computed tomography.ConclusionsGemella bergeri can be the causative pathogen of septic shock. If this pathogen cannot be identified manually or through commercial phenotypic methods, 16S rRNA gene sequencing should be considered.

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Sixth case of infective endocarditis caused by Gemella bergeri

Cited by 9 publications

References 3 publications

Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

First Case of Tricuspid Valve Endocarditis Caused byGemella bergeri

Purpura fulminans with Lemierre’s syndrome caused by Gemella bergeri and Eikenella corrodens: a case report

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