Sixteen gauge needles improve specimen quality but not cancer detection rate in transrectal ultrasound-guided 10-core prostate biopsies

Inal, Gurdal; Öztekin, Volkan; Uğurlu, Özgür; Kosan, Murat; Akdemir, Ozgur; Çetinkaya, Mesut

doi:10.1038/pcan.2008.34

Cited by 14 publications

(9 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings are not in line with a similar experience reported by Inal et al [5] who observed that the quality of samples was better using a 16-gauge needle. In both studies, fragmentation was one of the quality outcomes because it impedes to assess correctly the cancer quantity in sampling and to determine clearly the GS [13].…”

Section: Discussioncontrasting

confidence: 88%

See 1 more Smart Citation

Prostate Biopsy Quality Is Independent of Needle Size: A Randomized Single-Center Prospective Study

Cicione

Cantiello²,

Nunzio³

et al. 2012

Urol Int

View full text Add to dashboard Cite

Objective: To evaluate sample quality, prostate cancer detection rate and biopsy morbidity in transrectal ultrasound (TRUS)-guided prostate biopsy (PBx) using 16- or 18-gauge Tru-Cut needles. Patients and Methods: Patients undergoing TRUS PBx were consecutively randomized with a 1:1 ratio into two study arms: group A (16-gauge needle) and group B (18-gauge needle). Core fragmentation and small specimen length (<10 mm) rate were the sample quality criteria. Three consecutive visual analog scale tests for pain and the Clavien surgical classification complications grading for rectal bleeding were used to evaluate TRUS PBx morbidity. Results: Overall, 250 patients were evaluated. No statistically significant difference between 16- and 18-gauge biopsy needles was recorded for cancer detection rate (29.6 vs. 30.4%, p = 0.890), core fragmentation rate (5 vs. 7%, p = 0.425) and shorter specimen (2 vs. 2%, p = 0.309). Pain control was similar in the two groups during the biopsy, 30 min after biopsy and the evening of the same day. Very small or absent bleeding was the more frequent complication observed in each group. Conclusion: Prostate detection rate and sample quality were not influenced by needle size. A 16-gauge needle biopsy does not increase TRUS PBx morbidity.

show abstract

Section: Discussioncontrasting

confidence: 88%

“…On the other hand, it can potentially carry a higher risk of procedure-related complications. Few studies to date have addressed this specific issue [4,5]. …”

Section: Introductionmentioning

confidence: 99%

Prostate Biopsy Quality Is Independent of Needle Size: A Randomized Single-Center Prospective Study

Cicione

Cantiello²,

Nunzio³

et al. 2012

Urol Int

View full text Add to dashboard Cite

show abstract

“…The fragmentation of needle‐core biopsies complicates the interpretation of prostate biopsy cores. One contributing factor to fragmentation of needle cores during biopsy is the needle core length [1,2]. Little is known as to whether there are other controllable factors that contribute to fragmentation.…”

Section: Introductionmentioning

confidence: 99%

Fragmentation of prostatic needle biopsy cores containing adenocarcinoma: the role of specimen submission

Fajardo¹,

Epstein

2010

BJU International

View full text Add to dashboard Cite

Study Type – Diagnostic (case series) Level of Evidence 4 OBJECTIVE To determine the factors contributing to the fragmentation of prostatic core biopsies containing prostatic carcinoma, which might complicate the quantification of the number cores with cancer and/or the amount of tumour in a core. MATERIALS AND METHODS Prostate biopsy cases containing fragmented cores with cancer and cancer cases present only in unfragmented cores were sought in records from the consultant service of one of the authors. A ‘part’ corresponded to the site‐specific jar submitted by the urologist (i.e. left or right; left apex, left mid, etc.). Cases of prostatic adenocarcinoma with fragmented cores containing cancer (463) and cases with cancer lacking fragmented cores (200) were compared. RESULTS The mean number of parts per case was 8.1 and 7.5 in the unfragmented and fragmented cases, respectively (not significant). The mean number of cores per part was significantly higher in the fragmented group than the unfragmented group (2.6 vs 2.1, P = 0.004). The number of parts containing cancer was higher in cases with fragmented cores than in cases with unfragmented cores (2.8 vs 1.6, P < 0.001). A higher mean Gleason score was associated with the cancer in fragmented cores than in unfragmented cores (6.6 vs 6.2, P < 0.001). Multivariate regression analysis showed that fragmentation was associated with the number of parts with cancer (P < 0.001), cores per part (P < 0.001) and Gleason score (P < 0.04). CONCLUSIONS The number of parts per case with cancer, number of cores submitted per part, and Gleason score contribute to the likelihood of fragmentation of cores containing prostatic adenocarcinoma.

show abstract

“…Fink et al (28) reported that 16-gauge needles increased the cancer detection rate ex vivo. However, Inal et al (29) concluded that despite the fact that the mean core volume of the 16-gauge needle was almost twice that of the 18-gauge needle, cancer detection rates for the two groups were similar regarding the 10-core prostate biopsy procedures. The advantage of the 16-gauge needle was considered to be improved specimen quality as a result of acquiring less empty cores, small cores and fragmented cores.…”

Section: Discussionmentioning

confidence: 99%

Comparison Between a Combined Transrectal and Transperineal Approach and a Transrectal Approach for Prostate Rebiopsy

Shida

Hakariya

Takehara

et al. 2016

View full text Add to dashboard Cite

Abstract. Aim: To evaluate whether a combination method involving the transrectal (TR) and transperineal (TP)approach 1, 2, 3, 4 and 5 were 49.2% (551/1,119), 34.7% (75/216), 33.3% (20/60), 26.7% (4/15) Transrectal ultrasound (TRUS)-guided biopsy has been recognized as the standard method for confirming a prostate cancer diagnosis worldwide. The utility of magnetic resonance (MR)-guided biopsy has been indicated in recent reports (1, 2). We agree with the opinion, however, that discussion on TRUS biopsy is still important due to its cost and equipment. In short, we think that MR-guided biopsy is often difficult in developing countries. After the initial introduction of the sextant prostate biopsy technique proposed by Hodge (3), the TRUS-guided biopsy technique has evolved with the introduction of extended 10-to 12-core biopsy and, subsequently, to over 20-core saturation biopsy strategies to minimize the sampling error and improve the accuracy of prostate cancer detection (4). However, it is well-recognized that even the standard 12-core TRUS-guided biopsy can miss up to 30% of cancers (5). TRUS-guided biopsy predominantly targets the lateral and posterior peripheral gland and can miss anteriorly located cancers. Therefore, several studies have focused on methods for anterior and apical biopsies.Transperineal (TP) biopsy of the prostate is an alternative approach that is less frequently performed. Kakehi et al. (6) reviewed 212,065 biopsies carried out at 548 institutions during the period between 2004 and 2006 in Japan. Of the 212,065 biopsies, 76% were carried out using the transrectal (TR) approach, 23% using the TP approach and only 1% using the combined methods of TR and TP (TR+TP). Ong et al. (7) reported that TP biopsy accounted for <0.5% of all prostate biopsies performed in Australia in 2007. However, there has been increasing interest in TP biopsy in recent 4685This article is freely accessible online.

show abstract

Sixteen gauge needles improve specimen quality but not cancer detection rate in transrectal ultrasound-guided 10-core prostate biopsies

Cited by 14 publications

References 25 publications

Prostate Biopsy Quality Is Independent of Needle Size: A Randomized Single-Center Prospective Study

Prostate Biopsy Quality Is Independent of Needle Size: A Randomized Single-Center Prospective Study

Fragmentation of prostatic needle biopsy cores containing adenocarcinoma: the role of specimen submission

Comparison Between a Combined Transrectal and Transperineal Approach and a Transrectal Approach for Prostate Rebiopsy

Contact Info

Product

Resources

About