Six Years Follow-Up of Low-Level Laser Therapy (Lllt) in Patients With Age-Related Macular Degeneration (Amd).

Koev, K.; Avramov, L.; Borissova, Ekaterina

doi:10.21474/ijar01/5463

Cited by 1 publication

(1 citation statement)

References 15 publications

(24 reference statements)

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“…Recent reviews describe present understanding of the impact of red–infrared light on the resilience of the skin 14 and in inducing supernormal performance in muscle as well as accelerated recovery from fatigue and injury. 15,16 The use of PBM as a neuroprotectant was pioneered by Eells and colleagues 17 in a model of alcohol-induced degeneration of retinal photoreceptors and has been extended to the slowing of cerebral degenerations, 18–24 the mitigation of the effects of traumatic brain injury, 25–30 the mitigation of macular degeneration, 31,32 and improvements in the outcome of stroke. 33,34 The value of PBM for the mitigation of retinal damage in a range of conditions has received support from a recent meta-analysis 5 ; the author adds caution that larger scale clinical trials are needed for a fuller understanding of the mechanisms involved.…”

Section: Light and Other Radiationsmentioning

confidence: 99%

Acquired Resilience: An Evolved System of Tissue Protection in Mammals

et al. 2018

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This review brings together observations on the stress-induced regulation of resilience mechanisms in body tissues. It is argued that the stresses that induce tissue resilience in mammals arise from everyday sources: sunlight, food, lack of food, hypoxia and physical stresses. At low levels, these stresses induce an organised protective response in probably all tissues; and, at some higher level, cause tissue destruction. This pattern of response to stress is well known to toxicologists, who have termed it hormesis. The phenotypes of resilience are diverse and reports of stress-induced resilience are to be found in journals of neuroscience, sports medicine, cancer, healthy ageing, dementia, parkinsonism, ophthalmology and more. This diversity makes the proposing of a general concept of induced resilience a significant task, which this review attempts. We suggest that a system of stress-induced tissue resilience has evolved to enhance the survival of animals. By analogy with acquired immunity, we term this system ‘acquired resilience’. Evidence is reviewed that acquired resilience, like acquired immunity, fades with age. This fading is, we suggest, a major component of ageing. Understanding of acquired resilience may, we argue, open pathways for the maintenance of good health in the later decades of human life.

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