Six versus twelve hours of single-balloon catheter placement with oxytocin administration for labor induction: a randomized controlled trial

Lassey, Sarah C.; Haber, Hilary; Kanbergs, Alexa; Robinson, Julian N.; Little, Sarah E

doi:10.1016/j.ajog.2021.03.021

Cited by 15 publications

(18 citation statements)

References 10 publications

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“…This neural-humoral reflex is called Ferguson reflex. In clinical practice, while using OT to assist parturition remains controversial ( Litorp et al, 2021 ), induction of labor with a single-balloon catheter and OT results in a shorter time from insertion to delivery without increasing the rate of cesarean delivery ( Lassey et al, 2021 ). Thus, how to activate the mechanism underlying Ferguson reflex is worthy of investigation for augmentation of labor.…”

Section: Instinctive Behaviorsmentioning

confidence: 99%

Neural Functions of Hypothalamic Oxytocin and its Regulation

Wang

Liu

et al. 2022

ASN Neuro

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Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT over past decades, our understanding of its neural functions and their regulation remains incomplete. OT is mainly produced in OT neurons in the supraoptic nucleus (SON), paraventricular nucleus (PVN) and accessory nuclei between the SON and PVN. OT exerts neuromodulatory effects in the brain and spinal cord. While magnocellular OT neurons in the SON and PVN mainly innervate the pituitary and forebrain regions, and parvocellular OT neurons in the PVN innervate brainstem and spinal cord, the two sets of OT neurons have close interactions histologically and functionally. OT expression occurs at early life to promote mental and physical development, while its subsequent decrease in expression in later life stage accompanies aging and diseases. Adaptive changes in this OT system, however, take place under different conditions and upon the maturation of OT release machinery. OT can modulate social recognition and behaviors, learning and memory, emotion, reward, and other higher brain functions. OT also regulates eating and drinking, sleep and wakefulness, nociception and analgesia, sexual behavior, parturition, lactation and other instinctive behaviors. OT regulates the autonomic nervous system, and somatic and specialized senses. Notably, OT can have different modulatory effects on the same function under different conditions. Such divergence may derive from different neural connections, OT receptor gene dimorphism and methylation, and complex interactions with other hormones. In this review, brain functions of OT and their underlying neural mechanisms as well as the perspectives of their clinical usage are presented.

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Section: Instinctive Behaviorsmentioning

confidence: 99%

Neural Functions of Hypothalamic Oxytocin and its Regulation

Wang

Liu

et al. 2022

ASN Neuro

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“…The comparable studies by Bleicher et al [18] and Lassey et al [19] do not provide information on the timing of onset of the induction of labour. In our clinic, the start of the IOL using the double balloon catheter was changed from the evening hours at 8 pm for 12 hours to the morning at 8 am for 6 hours, so that the women were spared nighttime induction of labour.…”

Section: Discussionmentioning

confidence: 89%

Induction of Labour with a Double Balloon Catheter – Comparison of Effectiveness of Six Versus Twelve Hours Insertion Time: a Prospective Case Control Study

Strößner,

Heimann,

Schleußner

et al. 2023

Geburtshilfe Frauenheilkd

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Induction of labour is a common obstetric procedure to initiate or augment contractions when labour is delayed or uncertain. The double balloon catheter is a safe and effective mechanical method for cervical ripening during induction of labour. This study evaluates the effectiveness of reducing double balloon catheter insertion time from 12 to 6 hours.248 women undergoing induction with a double balloon catheter at term were divided into two groups: catheter placed for 12 hours at 8 pm in the first half of 2021 (P12) and catheter placed for 6 hours at 7 am in the second half of 2021 (P6). T-tests, chi-squared tests, and Wilcoxon signed rank test were used for statistical analysis. Primary and secondary endpoints included induction to delivery interval, prostaglandin to delivery interval, mode of delivery, and maternal and neonatal outcomes.The P6 group had a significantly reduced induction to delivery interval of 558 min (P6: 1348 min, P12: 1906 min, p < 0.01, 95% CI: 376–710) within demographically comparable groups. Multiparous women also showed a significant reduction in prostaglandin to delivery interval of 260 min (P6: 590 min, P12: 850 min, p = 0.038, 95% CI: 9–299). There were no significant differences in mode of delivery, maternal blood loss, or neonatal outcome.Reducing double balloon catheter placement time from 12 to 6 hours resulted in almost 9 hours less induction to delivery interval without adverse effects on maternal and neonatal outcome.

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“…When considering route of administration and number of doses required, several well-designed randomized controlled trials have demonstrated superiority of (12,676) 23 Higher rate of vaginal birth after CD among patients undergoing induction at 39 wk compared with expectant management (P < 0.001) Case report (1) 24 Misoprostol can cause excessive uterine activity and uterine rupture in TOLAC patients Case report (2) 25 Higher frequency of disruption of prior uterine incisions among patients undergoing induction with misoprostol in TOLAC patients Case reports (89) 26 Misoprostol increases the risk of uterine rupture in patients with a scarred uterus (P = 0.0001) Retrospective chart review (91) 27 Misoprostol induction of labor increases the risk of uterine rupture in patients with a history of CD (P = 0.0001) Evidence-based review 28 Rates of uterine rupture in midtrimester among patients with scarred uteri are <1%, although the impact of prostaglandin dose and dosing interval remains unclear Systematic review (16 studies) 29 The risk of uterine rupture among women with a prior CD undergoing second-trimester abortion using misoprostol is <0.3% Case report (1) 30 Uterine rupture can occur when misoprostol is used in the second trimester in a woman with a uterine scar 33 Balloon removal after 12 h associated with higher rate of vaginal delivery in 24 h compared with removal after 24 h (P < 0.001) RCT (177) 34 Balloon removal after 6 h demonstrated shorter time to delivery (P = 0.04) and no difference in CD rates compared with removal after 12 h RCT (197) 35 With a double-balloon device removal at 6 h demonstrated shortened time to delivery for nulliparous (P < 0.04) and multiparous patients (P = 0.003) and fewer antepartum fevers (P = 0.02) compared with removal at 12 h PROM population: maternal/fetal outcomes Meta-analysis (3759) 36 37 Increased risk of clinical chorioamnionitis in Foley plus oxytocin group compared with oxytocin alone (P < 0.01). No difference in other infectious morbidities RCT (128) 38 No difference in time from induction to delivery, rates of postpartum hemorrhage, chorioamnionitis, or epidural use between induction with concurrent Foley/oxytocin vs oxytocin alone Meta-analysis (2639) 39 No evidence that routine use of prophylactic antibiotics reduces risk of infection in patients with PROM Outpatient cervical ripening RCT (110) 40 Outpatient method reduced hospital stay with similar efficacy and safety as inpatient Foley RCT (126) 41 Outpatient method reduced time from admission to delivery compared with inpatient Foley (P < 0.01) RCT (163)…”

Section: Synthetic Prostaglandinsmentioning

confidence: 99%

Evidence Based Management of Labor

Zambrano Guevara,

Buckheit,

Kuller

et al. 2024

Obstetrical &Amp; Gynecological Survey

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Importance Induction of labor (IOL) is a common obstetric intervention. Augmentation of labor and active management of the second stage is frequently required in obstetric practice. However, techniques around labor and induction management vary widely. Evidence-based practice regarding induction and labor management can reduce birth complications such as infection and hemorrhage and decrease rates of cesarean delivery. Objective To review existing evidence on IOL and labor management strategies with respect to preparing for induction, cervical ripening, induction and augmentation, and second stage of labor techniques. Evidence acquisition Review of recent original research, review articles, and guidelines on IOL using PubMed (2000–2022). Results Preinduction, pelvic floor training and perineal massage reduce postpartum urinary incontinence and perineal trauma, respectively. Timely membrane sweeping (38 weeks) can promote spontaneous labor and prevent postterm inductions. Outpatient Foley bulb placement in low-risk nulliparous patients with planned IOL reduces time to delivery. Inpatient Foley bulb use beyond 6 to 12 hours shows no benefit. When synthetic prostaglandins are indicated, vaginal misoprostol should be preferred. For nulliparous patients and those with obesity, oxytocin should be titrated using a high-dose protocol. Once cervical dilation is complete, pushing should begin immediately. Warm compresses and perineal massage decrease risk of perineal trauma. Conclusion and relevance Several strategies exist to assist in successful IOL and promote vaginal delivery. Evidence-based strategies should be used to improve outcomes and decrease risk of complications and cesarean delivery. Recommendations should be shared across interdisciplinary team members, creating a model that promotes safe patient care. Target Audience Obstetricians and gynecologists, family physicians Learning Objectives Discuss the current evidence and best practices regarding prelabor interventions to improve delivery outcomes; describe evidence-based methods of cervical ripening; outline data-driven practices to progress induction; and explain methods to improve birth outcomes and reduce risks in the second stage of labor.

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Six versus twelve hours of single-balloon catheter placement with oxytocin administration for labor induction: a randomized controlled trial

Cited by 15 publications

References 10 publications

Neural Functions of Hypothalamic Oxytocin and its Regulation

Neural Functions of Hypothalamic Oxytocin and its Regulation

Induction of Labour with a Double Balloon Catheter – Comparison of Effectiveness of Six Versus Twelve Hours Insertion Time: a Prospective Case Control Study

Evidence Based Management of Labor

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