Six types of tea extracts attenuated high-fat diet-induced metabolic syndrome via modulating gut microbiota in rats

Gut microbiota-mediated associations of green tea and catechin intakes with glucose metabolism in individuals without type 2 diabetes mellitus: a four-season observational study with mediation analysis

“…P. excrementihominis is likely to rely on amino acids to support its metabolic activities and physiological functions (Ju et al 2019 ). Given that green tea contains large amounts of free amino acids (Zhou et al 2022 ), it would promote the growth of P. excrementihominis , but further studies are needed to clarify this association. Taken together, habitual green tea intake, but not intake of catechins or EGCG alone, may contribute to the modulation of specific gut microbiota species.…”

“…Recent animal experiments suggested that the antidiabetic effects of green tea and catechins are, at least partly, mediated by the gut microbiota (Li et al 2020 ; Zhang et al 2020 ; Wu et al 2021 ; Dey et al 2020 ; Park et al 2020 ; Chen et al 2019 ; Wang et al 2018 , 2022 ; Zhou et al 2022 ). Owing to their chemical complexity, catechins are poorly absorbed in the small intestine (Warden et al 2001 ); thus, high amounts of catechins reach the colon where they are degraded by specific gut bacteria (Gowd et al 2019 ).…”

“…The gut microbiota is capable of metabolizing high-molecular-weight catechins to produce biologically active metabolites (Santangelo et al 2019 ; Li et al 2021 ). Green tea and its catechins and/or metabolites may have important impacts on the gut microecology (Liu et al 2020 ; Zhou et al 2022 ). Green tea and catechins were reported to inhibit the growth of pathogenic bacteria, such as Clostridium spp.…”

Coffee Leaf Tea Extracts Improve Hyperuricemia Nephropathy and Its Associated Negative Effect in Gut Microbiota and Amino Acid Metabolism in Rats

“…15 One hour after PO and adenine treatment, NC and MC groups were treated with saline, and TE (300 mg/kg) was given to the TE group. The dose of TE was followed by the study of Zhou et al 17 At the end of the experiment, a 12 h urine sample was obtained by using metabolic cages. Fresh feces were collected for microbiological analysis.…”

Oolong tea of different years protects high-fat diet-fed mice against obesity by regulating lipid metabolism and modulating the gut microbiota

“…In contrast, the pathogenic bacteria (e.g., Blautia, Helicobacter, and Desulfovibrio) are toxic to their host, disturbing the intestinal barrier and contributing to relevant diseases. 9 In addition, researches on microbiota manipulation, such as microbiota transplantation in germ-free animals, suggest that gut microbiota may have a causal role in obesity. [10][11][12] Moreover, the gut microbiota may develop into a viable therapeutic target for pharmaceutical therapies in obesity.…”