Six-month outcomes and effect of pulmonary rehabilitation among patients hospitalized with COVID-19: a retrospective cohort study

Dun, Yaoshan; Liu, Chao; Ripley-Gonzalez, Jeffrey W.; Liu, Ping; Zhou, Nanjiang; Gong, Xun; You, Baiyang; Du, Yang; Liu, Jiyang; Li, Bo; Liu, Suixin

doi:10.1080/07853890.2021.2001043

Cited by 18 publications

(80 citation statements)

References 47 publications

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“…Among the 159 full-text articles assessed for eligibility, 124 were removed for different reasons further detailed in Figure 1 . Finally, 35 studies [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ] remained at the end of the study selection. As detailed in Figure 2 , the global score for the risks of bias in-between studies were found to be heterogeneous, ranging from 31% [ 65 ] to 88% [ 40 , 47 , 57 , 68 ].…”

Section: Resultsmentioning

confidence: 99%

“…The higher risk of bias was observed for the ‘blinding of participants/personnel’ parameter assessed as ‘moderate risk’ for 94% [ 35 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ] of the studies, and as ‘high risk’ for 6% of them [ 36 , 48 ]. The ‘analysis bias’ was the second most important bias, with 29% [ 35 , 39 , 40 , 47 , 48 , 51 , 57 , 58 , 63 , 68 ] of the studies considered ‘low risk’, 34% [ 37 , 41 , 42 , 43 , 45 , 49 , 54 , ...…”

Section: Resultsmentioning

confidence: 99%

“…The ‘analysis bias’ was the second most important bias, with 29% [ 35 , 39 , 40 , 47 , 48 , 51 , 57 , 58 , 63 , 68 ] of the studies considered ‘low risk’, 34% [ 37 , 41 , 42 , 43 , 45 , 49 , 54 , 59 , 60 , 61 , 64 , 69 ] ‘moderate risk’, and 37% [ 36 , 38 , 44 , 46 , 50 , 52 , 53 , 55 , 56 , 62 , 65 , 66 , 67 ] ‘high risk’. The lowest risk of bias was found for the detection bias with 100% [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53...…”

Section: Resultsmentioning

confidence: 99%

“…As reported in Table S2 , 23 [ 36 , 37 , 38 , 41 , 43 , 44 , 45 , 46 , 48 , 49 , 53 , 54 , 55 , 59 , 60 , 61 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ] studies were prospective, while 12 [ 35 , 39 , 40 , 42 , 47 , 50 , 51 , 52 , 56 , 57 , 58 , 62 ] were retrospective. Concerning the constitutions of the groups, 16 [ 36 , 37 , 38 , 40 , 41 , 43 , 47 , 51 , 52 , 57 , 58 , 59 , 64 , 66 , 68 , 69 ] studies were only constituted by a single group of COVID-19 patients during or the after acute phase (COV+), 5 [ 45 ,…”

Section: Resultsmentioning

confidence: 99%

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Systematic Review of COVID-19-Related Physical Activity-Based Rehabilitations: Benefits to Be Confirmed by More Robust Methodological Approaches

Bailly

Pélissier

Coudeyre

et al. 2022

IJERPH

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The first emergency was to receive and treat COVID-19 patients in their acute phase; today, there is a clear need to propose appropriate post-acute rehabilitation programs. The aim of this research was to systematically review the effects of physical activity programs in the recovery of post-COVID-19 patients. The literature search followed the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, was registered in the PROSPERO database (CRD42022289219), and was conducted between August and December 2021. A total of 35 studies out of the 1528 initially identified were finally included in the analysis. The systematic review clearly showed the health benefits of rehabilitation including physical activity in post-COVID-19 recovery, regardless of exercise modalities. These positive results were even observed using minor muscle re-mobilization for severe cases (i.e., postural changes, few steps—2 times/day) or using low volumes of exercise for mild-to-moderate cases (i.e., 120 min/week). A total of 97% of the 29 studies that performed statistical analyses demonstrated a significant increase in at least one parameter of functional capacity, and 96% of the 26 studies that statistically investigated the effects on the quality of life, mental health, and general state reported improvements. Yet, most of the studies were retrospective, uncontrolled, and enrolled aged people with comorbidities presented in severe forms of COVID-19. Physical activity programs, in addition to their high heterogeneity, remained poorly described in 83% of the studies and were part of a multidisciplinary program for 89% of the studies. Despite promising results, there is today a real need for prospective well-designed studies specifically assessing the effects of physical activity. In addition, it might appear relevant to propose standardized programs further considering the main characteristics of patients such as age, comorbidities, or the severity of COVID-19.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Systematic Review of COVID-19-Related Physical Activity-Based Rehabilitations: Benefits to Be Confirmed by More Robust Methodological Approaches

Bailly

Pélissier

Coudeyre

et al. 2022

IJERPH

View full text Add to dashboard Cite

show abstract

“…A small comparative study found pulmonary rehabilitation to be effective in improving the physical capacity of recoverees, as reflected by the 6MWT. [78] For 6MWT according to disease severity in individual studies see Supplemental Table 2. Cardiopulmonary stress testing (CPET) can potentially reveal the mechanisms leading to subjective symptoms in individuals with long COVID.…”

Section: Functional Testingmentioning

confidence: 99%