Six-Month Chemotherapy for Urogenital Tuberculosis

Skutil, V; Varsa, J.; Obsitník, M

doi:10.1159/000472484

Cited by 24 publications

(8 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Renal tuberculosis is treated primarily with medical rather than surgical therapy, and expert opinion is that a standard daily 6-month regimen (Table 2) is adequate [326][327][328][329]. If ureteral obstruction occurs, procedures to relieve the obstruction are indicated.…”

Section: Genitourinary Tuberculosismentioning

confidence: 99%

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Nahid

Dorman

Alipanah

et al. 2016

Clinical Infectious Diseases

1,052

821

View full text Add to dashboard Cite

The American Thoracic Society, Centers for Disease Control and Prevention, and Infectious Diseases Society of America jointly sponsored the development of this guideline for the treatment of drug-susceptible tuberculosis, which is also endorsed by the European Respiratory Society and the US National Tuberculosis Controllers Association. Representatives from the American Academy of Pediatrics, the Canadian Thoracic Society, the International Union Against Tuberculosis and Lung Disease, and the World Health Organization also participated in the development of the guideline. This guideline provides recommendations on the clinical and public health management of tuberculosis in children and adults in settings in which mycobacterial cultures, molecular and phenotypic drug susceptibility tests, and radiographic studies, among other diagnostic tools, are available on a routine basis. For all recommendations, literature reviews were performed, followed by discussion by an expert committee according to the Grading of Recommendations, Assessment, Development and Evaluation methodology. Given the public health implications of prompt diagnosis and effective management of tuberculosis, empiric multidrug treatment is initiated in almost all situations in which active tuberculosis is suspected. Additional characteristics such as presence of comorbidities, severity of disease, and response to treatment influence management decisions. Specific recommendations on the use of case management strategies (including directly observed therapy), regimen and dosing selection in adults and children (daily vs intermittent), treatment of tuberculosis in the presence of HIV infection (duration of tuberculosis treatment and timing of initiation of antiretroviral therapy), as well as treatment of extrapulmonary disease (central nervous system, pericardial among other sites) are provided. The development of more potent and better-tolerated drug regimens, optimization of drug exposure for the component drugs, optimal management of tuberculosis in special populations, identification of accurate biomarkers of treatment effect, and the assessment of new strategies for implementing regimens in the field remain key priority areas for research. See the full-text online version of the document for detailed discussion of the management of tuberculosis and recommendations for practice.

show abstract

Section: Genitourinary Tuberculosismentioning

confidence: 99%

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Nahid

Dorman

Alipanah

et al. 2016

Clinical Infectious Diseases

1,052

821

View full text Add to dashboard Cite

show abstract

“…Regarding the duration of the UTTB treatment, the expert recommendation is that a standard daily 6-month regimen is adequate [12,29,31,95,96]. In countries where new cases of tuberculosis are resistant to organisms (resistant to isoniazid ≥4%), it is recommended to use four drugs in the intensive phase: INH, RIF, PZA, and EMB [97][98][99][100][101].…”

Section: Medical Treatmentmentioning

confidence: 99%

Urinary Tract Tuberculosis

Amaya-Tapia¹,

Aguirre-Ávalos²

2018

Tuberculosis

View full text Add to dashboard Cite

Urinary tract tuberculosis (UTTB) is an insidious disease with non-specific constitutional symptoms that are often unrecognized and lead to delayed diagnosis. Advanced UTTB may cause loss of kidney function. In the majority of literature, UTTB is reviewed together with genital tuberculosis because often both sites are involved simultaneously; "Genitourinary tuberculosis" (GUTB) is the most common term used in the literature. However, the term may cause confusion because the clinical presentation and diagnosis approach is very different, and does not always occur simultaneously. UTTB is the term used here as we encountered tuberculosis involvement of urinary tract only. This book chapter is a comprehensive review of the epidemiology, pathophysiology, clinical presentation, diagnosis approach, and current treatment of this disease.

show abstract

“…Risikoländern (hohe Tuberkuloseinzidenz und -prävalenz), aber auch aus Ländern mit niedriger Neuerkrankungsrate wie Deutschland zur 7 Resistenzentwicklung von Erregern der TB gegen einzelne oder mehrere wirkungsstarke Antituberkulotika, die zwingend andere Medikamentenkombinationen, eine län-gere Behandlungsdauer und eine effektive Tuberkulosekontrolle erfordern [26,29]. Insgesamt wird jedoch bei unkomplizierten Fällen mit UGT ein 6-Monats-Regime angewandt [10,25]. Besonders zu beachten sind die Nebenwirkungen der Antituberkulotika.…”

Section: Medikamentöse Therapieunclassified

Urogenitaltuberkulose in Deutschland

Lenk¹

2011

Urologe

View full text Add to dashboard Cite

Genitourinary tuberculosis (GUTB) usually results from the reactivation of old, dormant tuberculous diseases by pathogens of the Mycobacterium tuberculosis complex. The diagnosis of tuberculosis of the urinary tract is based on the case history, the finding of pyuria in the absence of infection as judged by culture on routine media and by radiological imaging. A positive yellow egg culture and/or histological analysis of biopsy specimens possibly combined with the polymerase chain reaction (PCR) is still required in most patients to establish a definitive diagnosis of GUTB. Antituberculous drug treatment is based on an initial 2 month intensive phase with three or four drugs daily followed by a 4 month continuation phase with only two drugs. Surgery as a treatment option in GUTB might be indicated in complicated urinary tuberculosis. After antituberculous treatment of GUTB a follow-up surveillance over 5 years is recommended. Although the incidence of GUTB in Germany is relatively low, it is still necessary to impart and deepen scientific knowledge of the diagnosis and therapy of GUTB.

show abstract

Six-Month Chemotherapy for Urogenital Tuberculosis

Cited by 24 publications

References 10 publications

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Urinary Tract Tuberculosis

Urogenitaltuberkulose in Deutschland

Contact Info

Product

Resources

About