Relation between 6 minute walk test and spirometric parameters [FEV1 and FVC] in patients with COPD is investigated. There is no published data in India in this respect. Hospital based cross sectional study. Clinical COPD questionnaire score, Forced expiratory volume in first second (FEV1) and Forced expiratory volume (FVC), 6 minute walk distance and 6 minute walk work were calculated and compared. Data was analyzed by SPSS 11. It was observed that 11.1 % had overall clinical copd questionnaire (CCQ) score of more than 3; 62.2% had baseline PaO2 between 60-80 mm Hg;88.9% had baseline PaCO2 lower than or equal to 45 mm Hg; 53.3% had severe COPD according to GOLD spirometry criteria;13.3% had complication of Pulmonary artery hypertension; 64.5% walked more than 300 meters distance and 21.1% (8) of patients with severe copd had significant desaturation during walk test. There was low positive correlation with no statistical significance between FEV1 and 6 MWD (r= 0.280, p= 0.062) and between FVC and 6 minute walk distance(r= 0.289, p= 0.055). Demographic parameters like age, BMI, smoking score, spirometry and baseline paco2 were not correlating with 6 minute walk distance. BMI and FEV1 (forced expiratory volume) were more correlating with 6 minute walk work. Severity of airway obstruction or pulmonary artery hypertension was not predicting significant desaturation during walk test. Measuring walk distance alone is not sufficient for assessment of severity and functional status of COPD the patients. 6 minute walk work, which is the product of walk distance and body weight, is more correlating with severity of the disease.