2007
DOI: 10.2995/jacsurg.21.544
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Six cases of primary lung cancer producing granulocyte colony-stimulating factor; clinical and pathological analysis

Abstract: されており,その値は7 8. 0~2 1 5 0. 0p g / ml (c u t o f f 値は 1 8. 0p g / ml ,症例6のみは再発時の値) と上昇していた. さらに白血球数のみならず血小板数は3 7. 1~6 4. 0× 1 0 4 / n l ,C R P値も6. 9~2 1. 2mg / d l と上昇していた.腫 瘍マーカーは C E A ,S C C ,NS Eについて検討したが, 症例1で C E Aが8. 8n g / ml と,症例3で S C Cが1 6. 6n g / ml と上昇がみられたが,他の症例には有意な上昇は 認められなかった.さらに I n t e r l e u k i n-6 (I L-6 ,c u t o f f 値は8. 0p g / ml)を症例2,3に測定したが,症例2は 6 0. 0p g / ml ,症例3は4 7 5. 0p g / ml と上昇がみられた (T a b l e1) . 2 0(5 4 4) 日呼外会誌 2 1巻4号(2 0 0 7年5月

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Cited by 4 publications
(1 citation statement)
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“…The primary sites of G-CSF-producing tumors are lung, bladder, mesothelioma, gallbladder, liver, thyroid, and stomach [13]. They have a poor prognosis; the 1-year survival rate for G-CSF-producing lung carcinoma cases is 12-13% [14,15]. In our case, the G-CSF-producing metastatic tumor was detected only 8 months after pneumonectomy, although the pathological stage of the lung cancer was stage IB.…”
Section: Discussionmentioning
confidence: 71%
“…The primary sites of G-CSF-producing tumors are lung, bladder, mesothelioma, gallbladder, liver, thyroid, and stomach [13]. They have a poor prognosis; the 1-year survival rate for G-CSF-producing lung carcinoma cases is 12-13% [14,15]. In our case, the G-CSF-producing metastatic tumor was detected only 8 months after pneumonectomy, although the pathological stage of the lung cancer was stage IB.…”
Section: Discussionmentioning
confidence: 71%