Sites of origin and patterns of migration of vasotocin/mesotocin neurons in developing brain of the chick

Arnold-Aldea, Susan A.; Sterritt, Coreen

doi:10.1002/(sici)1097-4695(199609)31:1<103::aid-neu9>3.0.co;2-6

Cited by 8 publications

(12 citation statements)

References 25 publications

(17 reference statements)

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“…Notably, our data show that the hypothalamic component of the BSTM is also populated by mesotocinergic cells (containing mesotocin, MT, the homolog of oxytocin, Goodson et al 2012). Because of their continuity with those in the paraventricular hypothalamic nucleus, these MT cells may be produced in the SPV hypothalamic domain, as suggested in chicken by Arnold-Aldea and Sterritt (1996). The BSTM also contains vasotocin neurons (AVT, homolog of vasopressin; Goodson et al 2012), which may also originate in the SPV (Abellán et al 2013).…”

Section: Medial Extended Amygdala (Eame)mentioning

confidence: 85%

Genoarchitecture of the extended amygdala in zebra finch, and expression of FoxP2 in cell corridors of different genetic profile

et al. 2016

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We used a battery of genes encoding transcription factors (Pax6, Islet1, Nkx2.1, Lhx6, Lhx5, Lhx9, FoxP2) and neuropeptides to study the extended amygdala in developing zebra finches. We identified different components of the central extended amygdala comparable to those found in mice and chickens, including the intercalated amygdalar cells, the central amygdala, and the lateral bed nucleus of the stria terminalis. Many cells likely originate in the dorsal striatal domain, ventral striatal domain, or the pallidal domain, as is the case in mice and chickens. Moreover, a cell subpopulation of the central extended amygdala appears to originate in the prethalamic eminence. As a general principle, these different cells with specific genetic profiles and embryonic origin form separate or partially intermingled cell corridors along the extended amygdala, which may be involved in different functional pathways. In addition, we identified the medial amygdala of the zebra finch. Like in the chickens and mice, it is located in the subpallium and is rich in cells of pallido-preoptic origin, containing minor subpopulations of immigrant cells from the ventral pallium, alar hypothalamus and prethalamic eminence. We also proposed that the medial bed nucleus of the stria terminalis is composed of several parallel cell corridors with different genetic profile and embryonic origin: preoptic, pallidal, hypothalamic, and prethalamic. Several of these cell corridors with distinct origin express FoxP2, a transcription factor implicated in synaptic plasticity. Our results pave the way for studies using zebra finches to understand the neural basis of social behavior, in which the extended amygdala is involved.

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Section: Medial Extended Amygdala (Eame)mentioning

confidence: 85%

Genoarchitecture of the extended amygdala in zebra finch, and expression of FoxP2 in cell corridors of different genetic profile

et al. 2016

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“…In the present study, first parvicellular AVT-ir neurons were detected in the sexually dimorphic portions of the BnST from E12. This is two days later than the first immunoreactive perikarya were observed in the area of the BnST (nST) in chick embryo by Arnold-Aldea and Sterritt (1996). However, the antiserum used in their study, besides AVT, cross-reacted with another neurohypophyseal hormone mesotocin (MT).…”

Section: Discussionmentioning

confidence: 92%

“…The anatomical nomenclature used in this study to describe the brain structures corresponds to the atlas of chicken brain by Kuenzel and Masson (1988), except terms used to name different portions of the BnST (in atlas, nucleus of stria terminalis, nST). Two recently published reports (Arnold-Aldea and Sterritt, 1996;Jurkevich et al, 1997) provided evidence in the chicken for the presence of three groups of AVT synthesizing neurons in the area of the BnST. In both reports, AVT nuclei between the septal and dorsal hypothalamic areas were referred to as the BnST, although spatial location and size of these cells were obviously different.…”

Section: Anatomical Nomenclature Used In the Studymentioning

confidence: 99%

“…AVT-ir perikarya were not observed in the chicken hypothalamus before E7.25-E8 (Tennyson et al, 1986;Arnold-Aldea and Sterritt, 1996). In the traditional region of the BnST (labeled nST in older publications) where large ir AVT neurons occur, the first neurons immunoreactive for neurohypophyseal peptides were identified from E10 onward (Arnold-Aldea and Sterritt, 1996). Although in the latter study, embryos of both sexes were used, no attempt was made to follow the development of sexual differentiation of the AVT system, and more specifically, no mention was made of AVT parvicellular neurons found near the PVN.…”

mentioning

confidence: 92%

“…Products of the AVT gene transcription as well as immunoreactive AVT became detectable in brain extracts from embryonic day (E) 6 onward (Milewski et al, 1989;Mü hlbauer et al, 1993). AVT-ir perikarya were not observed in the chicken hypothalamus before E7.25-E8 (Tennyson et al, 1986;Arnold-Aldea and Sterritt, 1996). In the traditional region of the BnST (labeled nST in older publications) where large ir AVT neurons occur, the first neurons immunoreactive for neurohypophyseal peptides were identified from E10 onward (Arnold-Aldea and Sterritt, 1996).…”

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confidence: 98%

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Development of sexually dimorphic vasotocinergic system in the bed nucleus of stria terminalis in chickens

Jurkevich¹,

Barth²,

Kuenzel

et al. 1999

J. Comp. Neurol.

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The bed nucleus of stria terminalis (BnST) of the domestic fowl contains two groups of parvicellular vasotocinergic neurons that are sexually dimorphic. In adult cockerels, arginine vasotocin (AVT) synthesis is well expressed in the dorsolateral and ventromedial portions of the BnST, whereas in corresponding brain areas of hens, AVT synthesis is completely lacking. In the present study, in situ hybridization and immunocytochemical methods were used to compare the ontogeny of sexually dimorphic AVT gene expression in the BnST of male and female chickens from day 12 of embryonic development (E12) until the onset of sexual maturation. By E12, both parvicellular groups of AVT‐immunoreactive (AVT‐ir) perikarya in the developing BnST can be distinguished in some males, whereas in females their presence is questionable. A quantitative analysis, beginning at E14, showed that the parvicellular dorsolateral portion of the BnST of male embryos had more AVT perikarya compared with females. In contrast, no evident sex difference in distribution pattern and number of AVT mRNA containing neurons in this BnST portion was observable by in situ hybridization at E15. At E18, as well as on the first and second days posthatch (D1 and D2), no differences in the number of AVT synthesizing cells and intensity of immunoreactive staining in male versus female chickens were found. Between D2 and D7, the number of AVT‐ir cells in the BnST declined rapidly in both sexes until it disappeared completely in females before D35. In males, another increase in sexually dimorphic AVT‐ir cells and innervation of the lateral septum was associated with the onset of puberty and fully matched a pattern observed in adult fowls. These results demonstrate that the sexually dimorphic part of the AVT system undergoes sexual differentiation during early stages of ontogeny. J. Comp. Neurol. 408:46–60, 1999. © 1999 Wiley‐Liss, Inc.

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Regionalization of the anterior hypothalamus in the chick embryo

Caqueret

Coumailleau

Michaud

2005

Developmental Dynamics

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Loss-of-function experiments in mice have shown that the transcription factors Sim1, Otp, Sim2, and Brn2 form a cascade essential for the differentiation of neuroendocrine cells of the anterior hypothalamus that produce vasopressin, oxytocin, somatostatin (SS), thyrotropin-releasing hormone (TRH), and corticotropinreleasing hormone (CRH). Very little is known about how the differentiation of these cell types is regulated in chick. Here, we report the cloning of the chick homolog of Otp. Moreover, we have systematically compared the expression of Sim1, Sim2, Brn2, and Otp with that of the markers of terminal differentiation TRH, SS, CRH, vasotocin, and mesotocin during development of chick embryos. We have found that the cell types studied generally develop in domains expressing these transcriptional regulators but that the pattern of neuronal differentiation and the spatial distribution of some regulators were not the same as in mice. Our results provide a framework useful for the functional analysis of hypothalamus development in chick. Developmental Dynamics 233:652-658, 2005.

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Sites of origin and patterns of migration of vasotocin/mesotocin neurons in developing brain of the chick

Cited by 8 publications

References 25 publications

Genoarchitecture of the extended amygdala in zebra finch, and expression of FoxP2 in cell corridors of different genetic profile

Genoarchitecture of the extended amygdala in zebra finch, and expression of FoxP2 in cell corridors of different genetic profile

Development of sexually dimorphic vasotocinergic system in the bed nucleus of stria terminalis in chickens

Regionalization of the anterior hypothalamus in the chick embryo

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