Site of antegrade and retrograde functional right bundle branch block in the intact canine heart.

Glassman, Robert D.; Zipes, Douglas P.

doi:10.1161/01.cir.64.6.1277

Cited by 25 publications

(2 citation statements)

References 21 publications

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“…2 D) (Fig. 2 E) (3,17,23,24), although the present study cannot exclude a site within the HB (with longitudinal dissociation (25)(26)(27)(28). Studies in man have suggested (17,(29)(30)(31)(32), and canine studies by Moe et as was seen in this study.…”

Section: Resultssupporting

confidence: 40%

Effects of alternating cycle lengths on refractoriness of the His-Purkinje system.

Denker¹,

Lehmann²,

Mahmud³

et al. 1984

J. Clin. Invest.

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A s bstract. The effects ofalternating cycle lengths (bigeminal rhythm) on His-Purkinje system refractoriness were studied in 14 patients using His bundle and right bundle recordings. Programmed atrial stimulation at constant cycle length (method I) was scanned using the atrial extrastimulus technique (A2) and compared with an atrial cycle length of identical duration coupled to A2 on alternate beats (method II). The results showed that (a) despite shorter cycle length ofthe His-Purkinje system with method II due to effect of A2 on atrioventricular nodal conduction (699±90 vs. 743±87 ms, P < 0.001), the relative refractory period of the His-Purkinje system was always longer with method II (463±52 vs. 440±43 ms, P < 0.001). A similar increase also occurred in effective refractory period of the His-Purkinje system; (b) while functional right bundle branch block occurred in eight patients and functional left bundle branch block in two patients with method I, functional right bundle branch block occurred in all 14 patients and left bundle branch block in seven patients with method II; (c) in two patients where both functional right and left bundle branch block occurred with method I this never was manifest at identical degree of abbreviation of His-Purkinje system cycle length but was manifest at identical abbreviation in each of seven patients with method II; (d) site of conduction delay and/or block during functional right bundle branch block was always proximal, i.e., between the His bundle and right bundle recordings with both methods. During method II this resulted in shortening of the subsequent right bundle cycle length relative to the subsequent His bundle (and of necessity left bundle) cycle length.

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Section: Resultssupporting

confidence: 40%

Effects of alternating cycle lengths on refractoriness of the His-Purkinje system.

Denker¹,

Lehmann²,

Mahmud³

et al. 1984

J. Clin. Invest.

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show abstract

“…Persistence of anterograde functional block of one bundle branch due to repetitive retrograde concealed conduction of impulses propagating from the contralateral bundle branch initially was postulated by Gouaux and Ashman 1 in 1947 and subsequently corroborated experimentally by Moe et al 2 and by Glassman and Zipes. 3 This electrophysiologic phenomenon was termed a "linking" by Rosenbaum et al 4 in 1972. The term "linking" now is used to describe a general phenomenon in which functional block in one limb of a reentrant circuit is dynamically maintained by repetitive impulse interference or by repetitive impulse collision.…”

Section: Introductionmentioning

confidence: 99%