Sir Victor Horsley's 19th century operations at the National Hospital for Neurology and Neurosurgery, Queen Square

Uff, Chris; Frith, Daniel; Harrison, C. A.; Powell, Michael; Kitchen, Neil

doi:10.3171/2010.9.jns09731

Cited by 15 publications

(5 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Pioneers Of Modern Neurosurgerymentioning

confidence: 99%

“…Victor Horsley (1857-1916), probably the most important neurosurgeon of his time, was the first to use bone wax to stop bleeding after trepanation and craniotomy and created the first assumptions of the future stereotaxic method 43 . He was also the first to successfully surgically remove a spinal extramedullary tumor after a laminectomy in 1887 43 . He was the first surgeon to devote his career entirely to the study and surgical treatment of CNS diseases and the founder of the first independent neurosurgical department in the world founded in London in 1886.…”

Section: Pioneers Of Modern Neurosurgerymentioning

confidence: 99%

“…He was the first surgeon to devote his career entirely to the study and surgical treatment of CNS diseases and the founder of the first independent neurosurgical department in the world founded in London in 1886. (National Hospital, Queen Square, London) 39,43,44 .…”

Section: Pioneers Of Modern Neurosurgerymentioning

confidence: 99%

See 2 more Smart Citations

A Brief Review of the History of Global and Croatian Neurosurgery

Splavski

2023

J. appl. health sci. (Online)

View full text Add to dashboard Cite

Neurosurgery is the oldest, but also the youngest medical discipline. Namely, archaeological findings confirm the existence of cranial bone trepanations in the Late Stone Age, while neurosurgery as a separate discipline was founded only at the beginning of the 20th century. Descriptions of head/spinal injuries, and trepanations, date back to ancient Egypt (Edwin Smith papyrus) and physicians like Hippocrates, the Alexandrian school, and Galen, who described his classification of cranial fractures, perfected trepanation and contributed to neuroanatomy and physiology. Unfortunately, with his disappearance, the study of the central nervous system ceased during the next millennium. Medieval contribution to neurosurgery is due to the work of Arab and Persian physicians (Albucasis, Avicenna), who collected, preserved, and improved the medical knowledge of ancient times, including neuroscience. With the arrival of the Renaissance in the early 16th century, significant advances in anatomy, medicine, surgery, and neuroscience began. Berengario da Carpi, Andreas Vesalius, and Ambroise Paré stood out as progenitors of this era. During the 19th century, at a time of progress in medicine and surgery, preconditions were created for more extensive and long-lasting neurosurgical procedures, while the era of modern neurosurgery began in the early 20th century with the pioneering activities of MacEwan, Horsley, Cushing, Elsberg, Dandy and many others. Further progress in neurosurgery was made through the use of an operating microscope, which from 1965 marked the era of modern microneurosurgery, founded by Yaşargil. The beginnings of neurosurgical activity in Croatia date back to the end of the 19th century when Theodor Wickerhauser published a record of the first craniotomy done in our country in 1886. In conclusion, modern neurosurgery as one of the most advanced medical professions is based on the achievements of its historical leaders, and on the cutting-edge diagnostic and surgical armamentaria, together with the superior neurosurgical service organization.

show abstract

Section: Pioneers Of Modern Neurosurgerymentioning

confidence: 99%

Section: Pioneers Of Modern Neurosurgerymentioning

confidence: 99%

See 1 more Smart Citation

A Brief Review of the History of Global and Croatian Neurosurgery

Splavski

2023

J. appl. health sci. (Online)

View full text Add to dashboard Cite

show abstract

“…For a long time in the past, there were many misunderstandings about epilepsy, which were associated with religion or culture (Ali et al 2016 ). It was not until 1886 when Victor first reported on surgical treatment for post-traumatic epilepsy by performing a craniotomy, which is considered the first epilepsy surgery in history (Singh and Dua 2023 ; Uff et al 2011 ). Psychological and behavioral methods were also applied to observe and assess epilepsy (Shafran et al 2020 ; Haut et al 2019 ; Cross 2015 ).…”

Section: Introductionmentioning

confidence: 99%

Unraveling the Neural Circuits: Techniques, Opportunities and Challenges in Epilepsy Research

Xiao,

Li,

Kong

et al. 2024

Cell Mol Neurobiol

View full text Add to dashboard Cite

Epilepsy, a prevalent neurological disorder characterized by high morbidity, frequent recurrence, and potential drug resistance, profoundly affects millions of people globally. Understanding the microscopic mechanisms underlying seizures is crucial for effective epilepsy treatment, and a thorough understanding of the intricate neural circuits underlying epilepsy is vital for the development of targeted therapies and the enhancement of clinical outcomes. This review begins with an exploration of the historical evolution of techniques used in studying neural circuits related to epilepsy. It then provides an extensive overview of diverse techniques employed in this domain, discussing their fundamental principles, strengths, limitations, as well as their application. Additionally, the synthesis of multiple techniques to unveil the complexity of neural circuits is summarized. Finally, this review also presents targeted drug therapies associated with epileptic neural circuits. By providing a critical assessment of methodologies used in the study of epileptic neural circuits, this review seeks to enhance the understanding of these techniques, stimulate innovative approaches for unraveling epilepsy's complexities, and ultimately facilitate improved treatment and clinical translation for epilepsy. Graphical Abstract

show abstract

“…Awake craniotomy has been adopted for the surgical treatment of intractable epilepsy more than 100 years ago, and is now considered as a gold standard of care for resection of tumors, such as primarily gliomas, located within or close to the eloquent areas (i.e., sensorimotor or language areas) of the brain [ 1 , 2 ]. The modern awake craniotomy techniques have evolved in combination with intraoperative neurophysiologic monitoring to identify the eloquent areas of the brain.…”

Section: Introductionmentioning

confidence: 99%

Anesthetic considerations for awake craniotomy

Kim

Choi

2020

Anesth Pain Med

View full text Add to dashboard Cite

Awake craniotomy is a gold standard of care for resection of brain tumors located within or close to the eloquent areas. Both asleep-awake-asleep technique and monitored anesthesia care have been used effectively for awake craniotomy and the choice of optimal anesthetic approach is primarily based on the preferences of the anesthesiologist and surgical team. Propofol, remifentanil, dexmedetomidine, and scalp nerve block provide the reliable conditions for intraoperative brain mapping. Appropriate patient selection, adequate perioperative psychological support, and proper anesthetic management for individual patients in each stage of surgery are crucial for procedural safety, success, and patient satisfaction.

show abstract

Sir Victor Horsley's 19th century operations at the National Hospital for Neurology and Neurosurgery, Queen Square

Cited by 15 publications

References 8 publications

A Brief Review of the History of Global and Croatian Neurosurgery

A Brief Review of the History of Global and Croatian Neurosurgery

Unraveling the Neural Circuits: Techniques, Opportunities and Challenges in Epilepsy Research

Anesthetic considerations for awake craniotomy

Contact Info

Product

Resources

About