SiO2-based glass/bone interfacial reactions

Devitrification studies of wollastonite–tricalcium phosphate eutectic glass

“…The glass presents an adequate thermal expansion coefficient (a) to obtain materials with good mechanical stability [29][30][31][32][33].…”

“…To improve the ingrowth of new bone into implants (osteointegration), the use of materials with an appropriate interconnected porous structure has been recommended [5,[30][31][32][33]. The design of a porous ceramic implant material has the potential of controlling bone ingrowths.…”

Novel Bioactive Functionally Graded Coatings on Ti6Al4V

“…The experiments have shown that there is a narrow range of glass compositions in the SiO 2 ±CaO±MgO±Na 2 O± K 2 O±P 2 O 5 system that can be used to coat Ti or Ti6Al4V and that also form apatite (the mineral component of the bone) during in-vitro tests in simulated body fluid (SBF) (as displayed in Fig. [14] However, their CTE is too high compared to that of Ti and Ti6Al4V, and large thermal stresses are induced during processing, resulting in cracked coatings. [13] Glasses with silica contents above this range are able to form adherent coatings, but are not bioactive.…”

Stress–corrosion crack growth of Si–Na–K–Mg–Ca–P–O bioactive glasses in simulated human physiological environment

“…A new series of glasses in the family Na-K-Ca-Mg-P-Si-O (Table 1) have been prepared that show bioactivity to differing degrees either in vitro [12][13][14][15][16][17], or, in the case of 6P55, in vivo using rat models [18]. Glasses with silica contents larger than ∼ 60 wt% (e.g., 6P61) are not bioactive, but they are biocompatible [19,20].…”