Sinus mucosa thinning and perforation after sinus augmentation. A histological study in rabbits

Kato, Shingo; Botticelli, Daniele; Santis, Enzo De; Kanayama, Masatsugu; Ferreira, Sueli Mara Soares Pinto; Rangel‐Garcia, Idelmo

doi:10.1007/s10006-021-00946-y

Cited by 12 publications

(34 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several sinus mucosa perforations at the implant apex and threads were found in both groups. This is in agreement with another experiment in rabbits in which implants were simultaneously placed after bilateral sinus augmentation using either a deproteinized bovine bone mineral (DBBM) or autogenous bone (AB) collected from the tibia [ 32 ]. The healing was evaluated after 7 days and 40 days, six animals each period.…”

Section: Discussionsupporting

confidence: 89%

“…However, it also has to be considered that the DBBM granules were also associated with perforations of the sinus mucosa. After 7 days of healing, in that experiment [ 32 ], while no perforations in the AB particles were found, six perforations in two sinuses were observed in the DBBM granules. After 40 days of healing, three perforations of the mucosa in two sinuses were observed in association with DBBM granules, while no perforations were seen in the AB group, excluding those already described at the implants body.…”

Section: Discussionmentioning

confidence: 99%

“…However, if the placement of an implant simultaneously to sinus floor elevation without grafts will results in a protrusion of the implant apex beyond the new sinus floor, the next consequent question is about the fate of the sinus mucosa in such clinical conditions. The spontaneous perforation over time of the sinus mucosa after sinus augmentation has been documented in experimental studies at both implants [ 32 ] and graft particles [ 32 , 33 ] so that it might be speculated that implants placed simultaneously to sinus augmentation without graft might be exposed over time to a high rate of sinus mucosa perforations.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Argon Bioactivation of Implants Installed Simultaneously to Maxillary Sinus Lifting without Graft. An Experimental Study in Rabbits

Omori

Botticelli²,

Ferri³

et al. 2021

Dentistry Journal

Self Cite

View full text Add to dashboard Cite

Background: The treatment of the surface of titanium implants with argon plasma improved its hydrophilicity and cell adhesion, resulting in higher bone apposition on implant and graft surfaces. The spontaneous perforation over time of the sinus mucosa after sinus augmentation has been documented in experimental studies at both implants and graft particles. The aim of the present study was to evaluate the influence of plasma argon treatment of the implant surface on bone apposition and on the rate of sinus mucosa perforations. Methods: A sinus lifting procedure was performed bilaterally in sixteen rabbits, and implants, either treated with argon plasma or left without treatment (control), were placed simultaneously without grafts. After 8 weeks, histological analyses were carried out. Results: A collapse of the sinus mucosa was observed at all implants. Twenty-four out of thirty-two implants presented sinus mucosa perforations at the apex. Several perforations were also found at the threads. Thinned mucosa sites (width < 40 µm) were found around almost all implants. About 2.6–2.9 mm of the apical regions of the implant did not present signs of osseointegration and about 1.3 mm were exposed to the sinus cavity. No statistically significant differences were found between plasma and control sites. Conclusions: In conclusion, the sinus mucosa was damaged and perforated by direct contact with treated and non-treated implant surfaces. The treatment of the implant surface with argon plasma did not affect the outcomes.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Argon Bioactivation of Implants Installed Simultaneously to Maxillary Sinus Lifting without Graft. An Experimental Study in Rabbits

Omori

Botticelli²,

Ferri³

et al. 2021

Dentistry Journal

Self Cite

View full text Add to dashboard Cite

show abstract

“…However, the contribution of the sinus mucosa in increasing this "virtual mucosa thickness" is limited. The histological changes of the thickness of the mucosa after sinus augmentation were studied in rabbits [47,55]. The pristine sinus mucosa presented a thickness of about 70-80 µm in both studies.…”

Section: Limitations Of the Studymentioning

confidence: 99%

“…Between 2 and 8 weeks, the sinus mucosa increased the dimensions by about 100 µm, mainly due to gland proliferations. In another experiment [55], either deproteinized bovine bone mineral or autogenous bone were used as fillers. After seven and 40 days of healing, several regions of the sinus mucosa were found presenting a reduced mucosa thickness (<40 µm), especially in the DBBM group.…”

Section: Limitations Of the Studymentioning

confidence: 99%

Influence of Anatomical Parameters on the Dimensions of the Subantral Space and Sinus Mucosa Thickening after Sinus Floor Elevation. A Retrospective Cone Beam Computed Tomography Study

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background: Various anatomical parameters might influence the surgical approach for maxillary sinus floor elevation. The objective of the present study was to retrospectively evaluate the influence of anatomical parameters on the dimensions of the subantral space and of the sinus mucosa thickening after sinus floor elevation. Material and Methods: Seventy-eight maxillary sinuses in sixty-five patients were evaluated on cone beam computed tomographies taken before surgery and after one week (t1w) and nine months (t9m). Several parameters such as the distance XF between an axis parallel to the base of the nose (X-axes) and the sinus floor (F) were correlated with the height gain (IF) at t1w and t9m and the post-surgical edema. Results: A weak significant positive correlation was observed between height gain vs. sinus height of interest (XF), the balcony, and the sinus floor angle. The post-surgical edema was influenced by the initial mucosa thickness and the xenograft used. Conclusions: Various parameters might affect height gain and sinus mucosa thickening after sinus floor elevation. The height of interest, the balcony, and the sinus floor angle showed significant correlations with height gain. The initial thickness of the mucosa and the biomaterial used influenced the post-surgical edema.

show abstract

Mucosal adhesion phenomenon after maxillary sinus floor elevation: A preclinical study

Alccayhuaman

Botticelli

Lang

et al. 2023

Clinical Oral Implants Res

View full text Add to dashboard Cite

AimTo describe the histological events that occur after maxillary sinus floor elevation when the elevated and undetached sinus mucosa are in close proximity or in contact with each other.Materials and methodsFrom 76 rabbits, 152 elevated maxillary sinuses were analyzed histologically. Sites without adhesions were classified as “No proximity,” whereas the adhesion stages were divided into “Proximity,” “Fusion,” and “Synechia stages.” The width of the pseudostratified columnar epithelium and the distance between the two layers of the elevated and undetached sinus mucosae were measured at various standardized positions.ResultsThirty‐one sites presenting with adhesions were found. Twelve sites were in the proximity stage,” presenting cilia of the two epithelial layers that were shortened and interlinked within the mucous context. Hyperactivity of the goblet cells was also observed. In the other cases, the hyperplastic epithelium showed attempts to reach the contralateral mucosa. The 15 “fusion stage” sites presented regions with epithelial cells of the two mucosal layers that penetrated each other. Four sites presented “synechiae stages,” represented by bridges of connective tissue connecting the two lamina propria.ConclusionsClose proximity or tight contact between the elevated and undetached mucosa adhering to the bone walls might occur after maxillary sinus floor elevation. This induced hyperplasia of the epithelial cells and adhesion of the two layers until synechiae formation.

show abstract

Sinus mucosa thinning and perforation after sinus augmentation. A histological study in rabbits

Cited by 12 publications

References 36 publications

Argon Bioactivation of Implants Installed Simultaneously to Maxillary Sinus Lifting without Graft. An Experimental Study in Rabbits

Argon Bioactivation of Implants Installed Simultaneously to Maxillary Sinus Lifting without Graft. An Experimental Study in Rabbits

Influence of Anatomical Parameters on the Dimensions of the Subantral Space and Sinus Mucosa Thickening after Sinus Floor Elevation. A Retrospective Cone Beam Computed Tomography Study

Mucosal adhesion phenomenon after maxillary sinus floor elevation: A preclinical study

Contact Info

Product

Resources

About