Síntesis y caracterización de membranas híbridas a partir de quitosan, polivinil alcohol y sílice para su aplicación en deshidratación de gases

Gutiérrez-Gutiérrez, Martha Isabel; Morales-Mendivelso, Diego Francisco; Muvdi-Nova, Carlos Jesús; Chaves–Guerrero, Arlex

doi:10.15332/iteckne.v12i1.819

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Further, Figure S4 show the obtained differential scanning calorimetry (DSC) results, employed to perform a more detailed analysis of the possible phase changes at temperatures between 15 and 60 • C. However, no signals were recorded within the selected range, indicating the absence of thermal changes since thermal stability was indicated [50]. Regarding the degradation process itself, it has been observed that between 200 and 240 • C (depending on the formulation), the mass weight loss can be related to the detachment of lateral groups from the main molecule chains [51] to continue similar degradation behavior posteriorly. The data collected for the starting reagents are presented in Figure S3.…”

Section: Hydrogel Thermal Stability Analysismentioning

confidence: 99%

Mimicking the Physicochemical Properties of the Cornea: A Low-Cost Approximation Using Highly Available Biopolymers

Hernández,

Panadero-Medianero,

Arrázola

et al. 2024

Polymers

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Corneal diseases represent a significant global health challenge, often resulting in blindness, for which penetrating keratoplasty is the clinical gold standard. However, in cases involving compromised ocular surfaces or graft failure, osteo-odonto keratoprosthesis (OOKP) emerges as a vital yet costly and complex alternative. Thus, there is an urgent need to introduce soft biomaterials that mimic the corneal tissue, considering its translation’s physicochemical, biological, and economic costs. This study introduces a cross-linked mixture of economically viable biomaterials, including gelatin, chitosan, and poly-D-lysine, that mimic corneal properties. The physicochemical evaluation of certain mixtures, specifically gelatin, chitosan, and poly-D-lysine cross-linked with 0.10% glutaraldehyde, demonstrates that properties such as swelling, optical transmittance, and thermal degradation are comparable to those of native corneas. Additionally, constructs fabricated with poly-D-lysine exhibit good cytocompatibility with fibroblasts at 72 h. These findings suggest that low-cost biopolymers, particularly those incorporating poly-D-lysine, mimic specific corneal characteristics and have the potential to foster fibroblast survival. While further studies are required to reach a final corneal-mimicking solution, this study contributes to positioning low-cost reagents as possible alternatives to develop biomaterials with physicochemical properties like those of the human cornea.

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Section: Hydrogel Thermal Stability Analysismentioning

confidence: 99%