Sinonasal Teratocarcinosarcoma: A Rare Clinical Entity managed by Medial Maxillectomy and Adjuvant Chemoradiation

Gupta, Sumit; Naik, Sudhir M; Lnu, Nanjundappa; Halkud, Rajshekar; Lnu, Srihariprasad; Sidappa, KT; Rao, Clementina Rama

doi:10.5005/jp-journals-10013-1131

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…As such, many authors believe these tumors are not of germ cell origin but instead originate from totipotent cells in the olfactory fossa, although several other postulated theories exist regarding underlying histogenesis. Treatment is with multimodality therapy, most often reported through case reports and case series 1434,2014–2051 . However, despite the rarity of this tumor there have been two systematic reviews published, the most recent of which was published in January 2021 by Chapurin et al 2052 .…”

Section: Other Malignant Lesionsmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors

Kuan

Wang

Adappa

et al. 2024

Int Forum Allergy Rhinol

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BackgroundSinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represents a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and presents 48 thematic and histopathology‐based topics spanning the field.MethodsIn accordance with prior ICAR documents, ICSNT assigned each topic as an Evidence‐Based Review with Recommendations, Evidence‐Based Review, and Literature Review based on level of evidence. An international group of multidisciplinary author teams were assembled for the topic reviews using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses format, and completed sections underwent a thorough and iterative consensus‐building process. The final document underwent rigorous synthesis and review prior to publication.ResultsThe ICNST document consists of 4 major sections: general principles, benign neoplasms and lesions, malignant neoplasms, and quality of life and surveillance. It covers 48 conceptual and/or histopathology‐based topics relevant to sinonasal neoplasms and masses. Topics with a high level of evidence provided specific recommendations, while other areas summarized the current state of evidence. A final section highlights research opportunities and future directions, contributing to advancing knowledge and community intervention.ConclusionAs an embodiment of the multidisciplinary and collaborative model of care in sinonasal neoplasms and masses, ICSNT was designed as a comprehensive, international, and multidisciplinary collaborative endeavor. Its primary objective is to summarize the existing evidence in the field of sinonasal neoplasms and masses.This article is protected by copyright. All rights reserved

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Section: Other Malignant Lesionsmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors

Kuan

Wang

Adappa

et al. 2024

Int Forum Allergy Rhinol

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Teratocarcinosarcoma of the Nasal and Maxillary Sinus Mass- A Rare Case

Sandhu¹,

Grover²,

Banipal³

et al. 2019

jemds

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A 42-yr. old man presented with chief complaints of nasal blockage, nasal bleeding and later on pain in the eyes and headache and progress to nasal mass within period of 3 months. Routine haematological and biochemical investigations were done, which were normal at the time of presentation. Nasal endoscopy was done which showed nasal mass which bleeds on touch. A computed tomography (CT) scan face and neck revealed an inhomogenously enhancing soft tissue density lesion measuring 5.7*3.3*3.9 cm involving left maxillary sinus extending to left ethmoid sinus, left nasal cavity reaching up to posterior choana abutting the nasal septum (Figure 1).

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Sinonasal teratocarcinosarcoma treated with surgery followed by volumetric modulated radiotherapy: a case report with review of literature

et al. 2018

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Surgical excision along with use of postoperative radiotherapy forms an integral management of sinonasal teratocarcinosarcoma (SNTCS). However, given the rarity of the tumor, no standardised guidelines, dose, technique and target delineation exist especially in the era of modern radiation delivery techniques. This is a case of 55-year-old male diagnosed as SNTCS treated with radical ethmoidectomy followed by volumetric modulated radiotherapy, showing good local control and acceptable toxicity profile.

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Sinonasal Teratocarcinosarcoma: A Rare Clinical Entity managed by Medial Maxillectomy and Adjuvant Chemoradiation

Cited by 3 publications

References 21 publications

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors

Teratocarcinosarcoma of the Nasal and Maxillary Sinus Mass- A Rare Case

Sinonasal teratocarcinosarcoma treated with surgery followed by volumetric modulated radiotherapy: a case report with review of literature

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