Sinonasal Mucormycosis: Diagnosis Using Computed Tomography

Alam, Aftab; Chander, BN; Sabhikhi, G S; Bhatia, Mukul

doi:10.1016/s0377-1237(03)80018-7

Cited by 11 publications

(13 citation statements)

References 4 publications

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“…[ 1 5 ] It usually starts in the nasal mucosa or palate and extends to involve the paranasal sinuses. [ 2 3 ] From the sinuses, it then involves the retro-orbital region after spreading through either direct extension or through the lacrimal, angular, and ethmoidal vessels. [ 2 ] This once it invades the arteries leads to thrombosis of the blood vessels and causes necrosis of the hard and soft tissues.…”

Section: Discussionmentioning

confidence: 99%

“…In CT, it usually presents as an aggressive enhancing soft tissue mass that extends beyond the confines of the sinus cavity and shows extensive bone destruction. [ 3 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] Early and prompt diagnosis is very crucial in such cases because any delay in the initiation of treatment can be life threatening due to the ability of these fungi to invade the adjacent blood vessels and to embolize itself at distant organs including the brain. [ 3 ]…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Rare opportunistic bread mold fungal infection of maxillary sinus in a diabetic patient

Bhaskar

Chhabra

Kaushal³

et al. 2017

Int J App Basic Med Res

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Mucormycosis is a rare potentially fatal opportunistic fungal infection that affects human beings. Normally, a healthy is immune to such infections but there are some risk factors which predispose a person to mucormycosis, of which malnutrition and diabetes mellitus are the most common risk factors. India is the most commonly affected country by mucormycosis because of high proportion people with low socioeconomic status and diabetes mellitus. In diabetes mellitus, mucormycosis is more aggressive and fatal due to an impaired host defense mechanism. In spite of being a rare and fatal fungal infection, early diagnosis and prompt multidisciplinary treatment comprising control of underlying predisposing factor, surgical management, and medical management can be helpful in such cases.

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Section: Discussionmentioning

confidence: 99%

“…In CT, it usually presents as an aggressive enhancing soft tissue mass that extends beyond the confines of the sinus cavity and shows extensive bone destruction. [ 3 ]…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Rare opportunistic bread mold fungal infection of maxillary sinus in a diabetic patient

Bhaskar

Chhabra

Kaushal³

et al. 2017

Int J App Basic Med Res

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“…A variety of different causative organisms are responsible for paranasal mycosis, Aspergillus and Zygomycetes being the commonest. 1 The patients may have infection by one or more organisms. Reports of combined mucormycosis and aspergillosis infections limited to the oro-rhinocerebral region are very rare.…”

Section: Introductionmentioning

confidence: 99%

Sinonasal Mucormycosis with Fungal Ball: A Rare Case Report

Bal¹,

Gupta²,

Gupta³

2014

An International Journal Clinical Rhinology

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Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection by Aspergillus and Rhizopus sp. involving nose, paranasal sinuses and orbit in a 51 years old male patient diagnosed as diabetic on admission. He presented to ENT OPD with history of drooping of right upper eyelid, decreased vision right eye and deviation of angle of mouth to left side for 12 days. NCCT nose, PNS and orbit showed soft tissue density in right maxillary sinus, ethmoids and destruction of right inferior turbinate. MRI of nose, PNS and orbit revealed hypointense density in right maxillary and ethmoid sinuses on T1-weighted images and on T2-weighted; it was hyperintense. Patient underwent endoscopic debridement under general anesthesia and tissue was sent for microbiological and histopathological examination which confirmed presence of Aspergillus and Rhizopus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good.

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“…A variety of different causative organisms are responsible for paranasal mycosis, Aspergillus and Zygomycetes being the commonest [1]. …”

Section: Introductionmentioning

confidence: 99%

Coinfection byAspergillusand Zygomycetes Species in a Case of Acute Rhinosinusitis

Vaidya

Shah

2011

Case Reports in Otolaryngology

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Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection by Aspergillus and Rhizopus sp. involving nose, paranasal sinuses, orbit, and brain in a 68-year-old known hypertensive male. He was presented to ENT OPD with history of fever and intermittent headache since fifteen days along with history of right-sided nasal obstruction and proptosis since seven days. CT scan of brain and paranasal sinuses showed findings of pansinusitis with cellulitic changes in right orbit. MRI confirmed the same along with features of intracranial extension with focal meningitis in right frontotemporal region. Laboratory parameters did not conclude much except for leucocytosis and hyponatremia. Patient was taken for endoscopic debridement from nose and paranasal sinuses, and tissue was sent for microbiological and histopathological examination. Minced tissue was processed, and after 48 hrs of incubation two types of growth were identified, one was yellowish, granular, and powdery consistent with Aspergillus sp., and another was cottony and woolly consistent with Rhizopus sp. LCB mount confirmed presence of Aspergillus flavus and Rhizopus arrhizus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good.

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Sinonasal Mucormycosis: Diagnosis Using Computed Tomography

Cited by 11 publications

References 4 publications

Rare opportunistic bread mold fungal infection of maxillary sinus in a diabetic patient

Rare opportunistic bread mold fungal infection of maxillary sinus in a diabetic patient

Sinonasal Mucormycosis with Fungal Ball: A Rare Case Report

Coinfection byAspergillusand Zygomycetes Species in a Case of Acute Rhinosinusitis

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