Sinonasal Manifestations in Cystic Fibrosis

Oomen, Karin P. Q.; April, Max M.

doi:10.1155/2012/789572

Cited by 30 publications

(41 citation statements)

References 60 publications

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“…In children, findings such as demineralised bilateral uncinate processes and medial displacement of the lateral nasal wall in the CT of paranasal sinuses should raise the suspicion of CF 6. The CT scan of the paranasal sinuses in patients with CF, however, invariably shows anatomical alteration when compared with the non-CF population 14 25.…”

Section: Discussionmentioning

confidence: 99%

“…The CT scan of the paranasal sinuses in patients with CF, however, invariably shows anatomical alteration when compared with the non-CF population 14 25. Fortunately, there is no proven correlation between image findings with the chronic rhinosinusitis disease severity 6 9 14. Interestingly, one study has shown an inverse correlation between the endoscopic and the CT findings of the sinuses with the CF disease severity score, the Shwachman and Kulczycki scoring system 25.…”

Section: Discussionmentioning

confidence: 99%

“…This includes the first line management plan and the timing for FESS. Conventional management of chronic rhinosinusitis calls for medical management as the first line management, and FESS only for intractable disease 6 9 20. Nasal saline lavage has been shown to improve symptoms control in non-CF chronic rhinosinusitis 5 22.…”

Section: Discussionmentioning

confidence: 99%

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Paediatric nasal polyps in cystic fibrosis

et al. 2016

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Patients with cystic fibrosis (CF) are at increased risk of nasal polyps. We present the case of a 17-month-old Caucasian patient with CF who presented with hypertelorism causing cycloplegic astigmatism, right-sided mucoid discharge, snoring and noisy breathing. Imaging suggested bilateral mucoceles in the ethmoid sinuses. Intraoperatively, bilateral soft tissue masses were noted, and both posterior choanae were patent. Polypectomy and bilateral mega-antrostomies were performed. Histological examination revealed inflammatory nasal polyposis typical of CF. The role of early functional endoscopic sinus surgery (FESS) in children with CF nasal polyposis remains questionable as the recurrence rate is higher, and no improvement in pulmonary function has been shown. Our case, however, clearly demonstrates the beneficial upper airway symptom relief and normalisation of facial appearance following FESS in a child with this condition.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Paediatric nasal polyps in cystic fibrosis

et al. 2016

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“…Nasal irrigations, nasal steroids, antibiotic courses, nebulized antibiotics, chest physiotherapy, and exercises aid to clear the copious secretions and thwart infections [96]. …”

Section: Managementmentioning

confidence: 99%

Rhinosinusitis in Children

Shahid

2012

ISRN Otolaryngology

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Rhinosinusitis is the inflammation of the mucous membranes of nose and paranasal sinus(es). 5–13% of upper respiratory tract infections in children complicate into acute rhinosinusitis. Though not life threatening, it profoundly affects child's school performance and sleep pattern. If untreated, it could progress to chronic rhinosinusitis (CRS). The pathogens involved in perpetuation of CRS consist of multidrug-resistant mixed microflora. CRS is challenging to manage and could further extend to cause eye or intracranial complications. In children, CRS diagnosis is often either missed or incomprehensive. Due to this, morbidity and strain on healthcare budget are tremendous. Flexible fiberoptic endoscopy has revolutionized management of CRS. Its utility in children is being increasingly recognized. Optimal management entails specific appropriate antimicrobials as well as treatment of underlying causes. The aim is to normalize sinus anatomy and physiology and regain normal mucociliary function and clearance.

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“…Nasal irrigations, nasal steroids, antibiotic courses, nebulized antibiotics, chest physiotherapy, and exercises aid to clear the copious secretions and thwart infections [96]. (4) Immunodeficiencies.…”

Section: 1mentioning

confidence: 99%

Rhinosinusitis in Children

Clement¹,

Vlaminck²

Pediatric ENT

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Rhinosinusitis is the inflammation of the mucous membranes of nose and paranasal sinus(es). 5-13% of upper respiratory tract infections in children complicate into acute rhinosinusitis. Though not life threatening, it profoundly affects child's school performance and sleep pattern. If untreated, it could progress to chronic rhinosinusitis (CRS). The pathogens involved in perpetuation of CRS consist of multidrug-resistant mixed microflora. CRS is challenging to manage and could further extend to cause eye or intracranial complications. In children, CRS diagnosis is often either missed or incomprehensive. Due to this, morbidity and strain on healthcare budget are tremendous. Flexible fiberoptic endoscopy has revolutionized management of CRS. Its utility in children is being increasingly recognized. Optimal management entails specific appropriate antimicrobials as well as treatment of underlying causes. The aim is to normalize sinus anatomy and physiology and regain normal mucociliary function and clearance.

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Sinonasal Manifestations in Cystic Fibrosis

Cited by 30 publications

References 60 publications

Paediatric nasal polyps in cystic fibrosis

Paediatric nasal polyps in cystic fibrosis

Rhinosinusitis in Children

Rhinosinusitis in Children

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