Sinonasal Glomangiopericytoma

Abstract

Glomangiopericytoma (sinonasal-type hemangiopericytoma) is a rare tumor arising from the periyctes surrounding capillaries and accounts for less than 0.5% of all sinonasal tumors. It falls within the category of borderline and low-malignant-potential soft tissue tumors of the nose and paranasal sinuses. It is defined by the World Health Organization as a sinonasal tumor demonstrating a perivascular myoid phenotype. It was noted that when this lesion arose in the nasal cavity, it tended to behave in a more indolent fashion than its soft tissue counterpart, suggesting that sinonasal hemangiopericytomas represented a distinct entity. We report a case of a 68-year-old female patient diagnosed with glomangiopericytoma arising in the left sinonasal cavity and discussed the condition in terms of differential diagnosis.

Characteristics and prognosis of glomangiopericytomas: A systematic review

“…After full‐text assessment, 139 articles were also excluded: articles containing no histologic findings (n = 20), unclear histology (n = 10), duplicate cases (n = 3), cases not arising in the sinonasal tract (n = 21), other sinonasal tumors, such as solitary fibrous tumor (n = 39), glomus tumor (n = 27), myopericytoma (n = 3), fibroma (n = 1), papilloma (n = 1), and lymphoma (n = 1), and reviews without information about individual cases (n = 13). Finally, 80 articles containing glomangiopericytoma of the sinonasal tract (337 cases) were identified as eligible for this study . Most articles (75/80; 94%) were published in English, except for 5 articles written in Korean …”

Sinonasal Glomangiopericytoma: A Case Report and Literature Review

“…Except for two review articles, we thoroughly reviewed these articles (20 cases including our case) on the basis of age/sex, location, associated diseases, clinical symptoms, endoscopic findings, image findings, pathology, and treatment. 1,[3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]…”

An unusual mass of nasal cavity: recurrent glomangiopericytoma

“…Histopathological and clinical differences make glomangiopericytomas a different entity. [7] Glomangiopericytomas are rare tumors and account for 0.5% of all sinonasal tumors. They have a very slight female preponderance and a peak incidence in the sixth and seventh decade of life.…”

“…On differential diagnosis, glomangiopericytomas do not stain for demsin, S100, CD34, but do for SMA and vimentin. [2,5,7] The gold standard treatment of glomangiopericytomas is total surgical removal of the mass with tumor-free margins. [13] An endoscopic approach is generally preferred instead of much more invasive approaches.…”

“…[9] Glomangiopericytomas generally originate in the nasal cavity and may extend to the paranasal sinuses, although isolated paranasal sinus involvements have been reported. [7] After examination, imaging techniques must be carried out for differential diagnosis of mass lesions of the nasal cavity. Computed tomography scanning is always carried out and magnetic resonance imaging scanning may be necessary in some situations.…”