Sinonasal Ewing sarcoma misdiagnosed as recurrent glomangiopericytoma: Case report and literature review

Huang, Alice E.; Hwang, Peter H.; Lin, Jonathan H.; Chang, Michael T.

doi:10.1016/j.xocr.2021.100369

Cited by 1 publication

(2 citation statements)

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“…The differential diagnosis includes vascular tumors such as glomus tumors, hemangiomas, pyogenic granulomas, and nasopharyngeal angiofibromas and soft tissue tumors such as solitary fibrous tumors (SFTs), desmoid-type fibromatosis, and Ewing sarcoma. 7,8 GPCs typically stain positive for nuclear betacatenin, which can differentiate them from glomus tumors, SFTs, lobular capillary hemangioma, and Ewing sarcomas and negative for STAT6 which can further differentiate them from SFTs. Meningiomas can arise in the middle ear region and are also on the differential diagnosis, but they typically show a nested, lobular arrangement of ovoid tumor cells that are separated by delicate fibrovascular stroma.…”

Section: Discussionmentioning

confidence: 99%

“…Histologically, GPCs appear as round or spindled cells in a perivascular distribution and stain positive for smooth muscle actin. The differential diagnosis includes vascular tumors such as glomus tumors, hemangiomas, pyogenic granulomas, and nasopharyngeal angiofibromas and soft tissue tumors such as solitary fibrous tumors (SFTs), desmoid‐type fibromatosis, and Ewing sarcoma 7,8 . GPCs typically stain positive for nuclear beta‐catenin, which can differentiate them from glomus tumors, SFTs, lobular capillary hemangioma, and Ewing sarcomas and negative for STAT6 which can further differentiate them from SFTs.…”

Section: Discussionmentioning

confidence: 99%

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Glomangiopericytoma Presenting as a Middle Ear Mass

Liu,

Berry,

Soltys

et al. 2023

The Laryngoscope

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We describe an unusual case of glomangiopericytoma presenting as a mass filling the middle ear, enveloping the ossicles, and extending into the mastoid antrum without bony destruction. Management involved three surgeries and stereotactic radiosurgery, which achieved short‐term local control with no evidence of disease on MRI imaging 12 months after radiation. Facial nerve function and hearing were preserved. This is the first report to our knowledge of a glomangiopericytoma presenting as a primary temporal bone lesion. Treatment with surgery and stereotactic radiosurgery for residual or recurrent disease is a reasonable approach to achieve local control and functional preservation. Laryngoscope, 2023

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%