Singlet oxygen oxidation of pyrroles: Synthesis and chemical transformations of novel 4,4-bis(trifluoromethyl)imidazoline analogs

Amplified Production of Singlet Oxygen in Aqueous Solution Using Metal Enhancement Effects

“…Singlet oxygen ( 1 O 2 ) is a reactive oxygen species that has been reported countless times in the literature as an important tool to induce oxidative damage in biological systems (24)(25)(26). As 1 O 2 is the excited form of molecular oxygen, with a finite lifetime of 10 À6 -10 À3 s in solution (27,28), and is highly reactive, it has been used in a broad range of applications including organic chemical synthesis (29)(30)(31), wastewater treatment (28,32,33) and photodynamic therapy (34)(35)(36). Interestingly, it has been shown that the metal enhancement effect is not limited to fluorescence, and enhancement of both 1 O 2 production, and phosphorescence quantum yield have been observed (12,(37)(38)(39)(40)(41)(42).…”

Green Synthesis of 1,3‐Dibenzylimidazolidine‐2,4,5‐triones by Oxidation of Hexabenzylhexaazaisowurtzitanes

“…One example of such a heterocycle comprises imidazoline and imidazolidine. Imidazolines are biologically active pharmacophores and synthetic intermediates in medicinal chemistry . Another member of this family is imidazolidine‐2,4,5‐trione (commonly known as parabanic acid) and its derivatives; they are used in preparation of alkylidene and imino‐substituted hydantoins by their reactions with Wittig reagents .…”

Trichloroisocyanuric acid as an efficient homogeneous catalyst for the chemoselective synthesis of 2-substituted oxazolines, imidazolines and thiazolines under solvent-free condition

“…1,2 Many derivatives of these heterocycles have shown antihypertensive, 3,4 antidepressive, 5 antihypercholesterolemic, 6 antidiabetic, 7 antitumor 8 and anti-inflammatory 9 properties. This importance is due to their great applications in medicine.…”