Single Vital-capacity and Successive Tidal-volume Breathing of Sevoflurane in Induction of Anesthesia for Tracheal Intubation in Gynecologic Patients

Lin, Tzu-Chen; Lu, Chih-Cherng; Kuo, Chi-Kun; Hsu, Che-Hao; Huang, Go-Shine; Liu, Jah‐Yao; Ho, Shung‐Tai

doi:10.1016/s1875-4597(08)60028-4

Cited by 11 publications

(10 citation statements)

References 17 publications

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“…For the calculation, one time constant is derived from the value of the FRC divided by the minute alveolar ventilation. Assuming that the FRC is equal to 2,400 mL in Taiwanese female adults in the supine position (14,15) and the mean alveolar ventilation in the hypoventilation group is 1.793 ml min -1 , one time constant for the FRC wash-in should be 1.39 minutes (2400 ml/1793 ml min -1 ) (16-18). The time needed to achieve 99% FRC filling was therefore 7.0 minutes (1.34 minutes × 5 time constants) in the hypoventilation group.…”

Section: Discussionmentioning

confidence: 99%

Hyperventilation accelerates the rise of arterial blood concentrations of desflurane in gynecologic patients

Lu¹,

Lin²,

Hsu³

et al. 2012

Clinics

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OBJECTIVES:Under a constant inspired concentration, the uptake of a volatile anesthetic into the arterial blood should mainly be governed by alveolar ventilation, according to the assumption that the patient's cardiac output remains stable during anesthesia. We investigated whether ventilation volume affects the rate of desflurane uptake by examining arterial blood concentrations.METHOD:Thirty female patients were randomly allocated into the following three groups: hyperventilation, normal ventilation and hypoventilation. Hemodynamic variables were measured using a Finometer, inspiratory and end-tidal concentrations of desflurane were measured by infrared analysis, and the desflurane concentration in the arterial blood (Ades) was analyzed by gas chromatography.RESULTS:During the first 10 minutes after the administration of desflurane, the Ades was highest in the hyperventilation group, and this value was significantly different from those obtained for the normal and hypoventilation groups. In addition, hyperventilation significantly increased the slope of Ades-over-time during the first 5 minutes compared with patients experiencing normal ventilation and hypoventilation, but there were no differences in these slopes during the periods from 5-10, 10-20 and 20-40 minutes after the administration of desflurane. This finding indicates that there were no differences in desflurane uptake between the three groups after the first 5 minutes within desflurane administration.CONCLUSIONS:Hyperventilation accelerated the rate of the rise in Ades following desflurane administration, which was time-dependent with respect to different alveolar ventilations levels.

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Section: Discussionmentioning

confidence: 99%

Hyperventilation accelerates the rise of arterial blood concentrations of desflurane in gynecologic patients

Lu¹,

Lin²,

Hsu³

et al. 2012

Clinics

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“…8 McClelland stated that in obstetric patients volatile anaesthetic induction can be used in place of intravenous induction. 9 Kirkbride DA et al observed that sevoflurane induction in elderly patients is well tolerated and mean arterial pressure is maintained.…”

Section: Discussionmentioning

confidence: 99%

A comparative study of sevoflurane induction using continuous tidal volume breaths versus three vital capacity breaths technique in adult patients undergoing elective surgical procedures under general anaesthesia

Manik¹,

Dhama²,

Subhash³

et al. 2020

IJCA

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Introduction: Previous studies have shown stable cardiovascular parameters and minimal airway irritation with sevoflurane induction in adults. Also, time taken for induction is comparable to intravenous drugs. The authors planned to conduct a randomized, control study to compare the effect of continuous tidal volume breaths versus three vital capacity breaths for sevoflurane induction on time taken for induction, haemodynamic parameters and intubating conditions in adult patients undergoing elective surgery under general anaesthesia. Materials and Methods: Sixty patients planned to undergo elective surgical procedures under general anaesthesia were included in study. Patients were divided randomly using sealed opaque envelope method in group 1 and group 2 of thirty patients each. Group 1 patients received continuous tidal volume breath and group 2 patients received three vital capacity breaths. The statistical analysis was done using IBM SPSS Statistics Software Version 15.0. The independent samples Student t-test was used to determine the differences in basic clinical characteristics, mean Arterial Pressure, heart Rate, and intubation time between the two groups. Quantitative data were evaluated by chi square test. Any p value less than 0.05 was considered as significant. Result: Variation in heart rate between two groups was statistically significant at 1 min. (p=0.04), 2 min. (p=0.01) and 3 min. (p=0.004) after start of induction. The time taken for loss of consciousness was significantly less in vital capacity induction group. (p <0.001) Intubating conditions were better in group2 (optimal, good in 90% and 10% participants respectively) as compared to group1 (optimal, good in 76.67% and 23.33% participants respectively). Conclusion: Heart rate and mean arterial pressure remain stable during sevoflurane induction in adult patients using three vital capacity breath or tidal volume breath technique. Intubating conditions are better and time taken to lose consciousness is less with vital capacity breaths.

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“…Sevoflurane has been used widely as inhalation induction agent for pediatric and adults anesthesia 1-3, in which requiring a high fresh gas flow to be used to rapidly increase the circuit anesthetic concentration. Compound-A production during induction may be dependent on the rate of fresh gas flow and the concentration of sevoflurane used.…”

Section: Discussionmentioning

confidence: 99%

Sofnolime with Different Water Content Causes Different Effects in Two Sevoflurane Inhalational Induction Techniques with Respect to the Output of Compound-A

Liu¹,

Li²,

Sun³

et al. 2012

Int. J. Med. Sci.

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Objective: During sevoflurane anesthesia with Sofnolime for CO2 absorption, the factors affecting the production of compound A (a chemical is nepherotoxic) are still not clear. This study is designed to investigate the effects of different fresh gas flow during induction, the vital capacity induction (VCI) vs. the tidal volume breath induction (TBI) on the compound-A production with a fresh Sofnolime or a dehydrated Sofnolime using a simulated lung model.Method: The experiments were randomly divided into four groups: group one, VCIf, vital capacity fresh gas inflow with fresh Sofnolime; group two, TBIf, tidal volume breath fresh gas inflow with fresh Sofnolime; group three, VCId, vital capacity fresh gas inflow with dehydrated Sofnolime, and group four, TBId, tidal volume breath fresh gas inflow with dehydrated Sofnolime. The inspired sevoflurane was maintained at 8%, the concentrations of compound-A were assayed using Gas-spectrum technique, and Sofnolime temperatures were monitored at 1-min intervals throughout the experiment.Results: The mean and maximum concentrations of compound A were significantly higher in the vital capacity group than the tidal volume breath group (P<0.01). At the beginning of anesthesia maintenance, the compound-A concentration in group VCIf was 36.28±6.13 ppm, which was significantly higher than the 27.32±4.21 ppm observed in group TBIf (P<0.01). However, these values decreased to approximately 2 ppm in the dehydrated Sofnolime groups. Sofnolime temperatures increased rapidly in the dehydrated Sofnolime groups but slowly in the fresh Sofnolime groups.Conclusion: With fresh Sofnolime, vital capacity induction increased compound-A production in the circuit system compared with tidal volume breath induction. However, with dehydrated Sofnolime, the effects of the two inhalation induction techniques on compound-A output were not significantly different.

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Single Vital-capacity and Successive Tidal-volume Breathing of Sevoflurane in Induction of Anesthesia for Tracheal Intubation in Gynecologic Patients

Cited by 11 publications

References 17 publications

Hyperventilation accelerates the rise of arterial blood concentrations of desflurane in gynecologic patients

Hyperventilation accelerates the rise of arterial blood concentrations of desflurane in gynecologic patients

A comparative study of sevoflurane induction using continuous tidal volume breaths versus three vital capacity breaths technique in adult patients undergoing elective surgical procedures under general anaesthesia

Sofnolime with Different Water Content Causes Different Effects in Two Sevoflurane Inhalational Induction Techniques with Respect to the Output of Compound-A

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