Single stage sternal reconstruction using titanium mesh for dehiscence following open-heart surgery

Dimarakis, Ioannis; Oswal, Dilip; Nair, Unnikrishnan

doi:10.1510/icvts.2004.096065

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…A field, which is ideal for scaffold-only techniques, saw a stealth development in the past 10 years [58,59]. Chest-wall and pericardium prosthesis, and application of biodegradable or nonabsorbable materials are per se tissue engineering issues.…”

Section: Chest-wall Structures and Pleural Surfacesmentioning

confidence: 99%

Tissue engineering and biotechnology in general thoracic surgery

Molnár

Pongrácz

2010

European Journal of Cardio-Thoracic Surgery

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Public interest in the recent progress of tissue engineering, a special line of biotechnology, makes the current review on thoracic surgery highly relevant. In this article, techniques, materials and cellular processes are discussed alongside their potential applications in tissue repair. Different applications of tissue engineering in tracheo-bronchial replacement, lung tissue cultures and chest-wall reconstruction are also summarised in the article. Potential tissue engineering-based solutions for destructive, chronic lung-injury-related conditions and replacement of tubular structures in the central airways are also examined.

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Section: Chest-wall Structures and Pleural Surfacesmentioning

confidence: 99%

Tissue engineering and biotechnology in general thoracic surgery

Molnár

Pongrácz

2010

European Journal of Cardio-Thoracic Surgery

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“…Sternal wound complications, including dehiscence and infection, remain challenging and occur in 1%–3% of patients undergoing cardiac surgery. This process leads to a variable mortality rate ranging from 14% to 47% [7]-[9]. Several techniques have been proposed for maximizing sternal stability in high-risk patients [10]-[15].…”

Section: Introductionmentioning

confidence: 99%

Straight versus S-shaped sternotomy: a histologic study in the sheep model

İnan

Küçükdurmaz

Karakan³

et al. 2014

J Cardiothorac Surg

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IntroductionStraight sternotomy is the most common access for open heart surgery. Techniques have been proposed for maximizing sternal stability in high-risk patients. This trend implies a growing need for newer surgical techniques. The aim of this experimental study in the sheep model is to evaluate median vs. S shaped sternotomy the feasibility of using a special device to accelerate the sternal instability and bone healing.Materials and methodsWe enrolled 31 sheep, weighing 18–30 kg. For all animals a midline skin incision was made. In group I (n = 16 animals), straight median sternotomy and in group II (n = 15 animals), S-shaped incision was marked on the periosteum of the sternum by new created device for standard S-shaped sternotomy. Sternum biopsies were performed on second surgery month for all survived animals from the sternum and the surrounding soft tissue.ResultsNo early superficial wound complications were observed. Overall mortality in the initial approach group was 19.3% (6 sheep). In group I; 3 sheep had died on first surgery day, the reason may be hemorrhage and in group II; 3 sheep developed intractable VF during surgery procedure or immediately afterwards so died. There were statistically significant differences in the scores of bone healing between group 1 and group 2 (4.2 vs.7.3, ANOVA, p < 0.001).DiscussionOur work is based on the use of a standard S-shaped sternotomy procedure on sheep sternum. In our experience with the sternal healing in the sheep model, the process of new bone formation was accelerated with S- shaped cut than straight sternotomy procedure.Electronic supplementary materialThe online version of this article (doi:10.1186/s13019-014-0173-x) contains supplementary material, which is available to authorized users.

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