Single session of laser photobiomodulation for symptom management of oral lichen planus: a retrospective study

Roccon, Andrea; Cavallin, Francesco; Zanette, Gastone; Bacci, Christian

doi:10.1007/s10103-023-03706-4

Cited by 2 publications

(1 citation statement)

References 41 publications

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“…However, a recent paper reported that a single session of laser PBM may be safe and effective in reducing pain for symptomatic OLP patients. 30 However, the study did not have any control arm; hence, further, randomized controlled studies with placebo or topical corticosteroids as a comparison would be necessary to provide sound evidence on the utility of the single session on PBMT. Wavelength is also considered one of the most critical factors in all types of phototherapy, and the recommended wavelength should be 600 and 700 nm to treat superficial tissue.…”

Section: Discussionmentioning

confidence: 99%

Photobiomodulation Therapy in the Management of Oral Lichen Planus: A Systematic Review and Meta-Analysis

Soh,

Cheah,

Veettil

et al. 2024

Eur J Dent

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Photobiomodulation therapy (PBMT) is a non-invasive and the latest form of therapy used in the treatment of non oncological diseases as well as cancers of various types and locations. The aim of this study was to systematically review and assess the efficacy of PBMT in managing oral lichen planus (OLP) compared to the interventions. A systematic review and meta-analysis were implemented according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. An electronic search using PubMed, Scopus, and Cochrane was conducted to retrieve relevant studies published until June 2023. The outcomes evaluated included the reduction in pain score and clinical severity scores (Prospero No CRD42023428626). A total of eight studies were identified for qualitative synthesis. The pooled analysis incorporating six studies revealed that there are no significant differences for both mean pain score (mean difference [MD] = 0.21, 95% confidence interval [CI] = −0.51, 0.93) as well as clinical score (MD = −0.08, 95% CI = −0.4, 0.25) between PBMT and comparison groups. Subgroup analysis based on corticosteroids as controls showed that there was no significant difference in mean reduction in pain score between PBMT and topical steroids (MD = 0.38, 95% CI = −0.54, 1.31). PBMT is as effective as other interventions in the treatment of OLP, though not superior, and can be a promising alternative treatment for cases resistant to steroids or when steroids are contraindicated. Further studies are recommended to standardize the optimal settings for the treatment of OLP.

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Section: Discussionmentioning

confidence: 99%