Single protein molecules separation, tracking and counting in ultra-thin silicon channels
Shilo Ohayon,
Liran Taib,
Navneet Chandra Verma
et al.
Abstract:Emerging single-molecule protein sensing techniques are ushering in a transformative era in biomedical research. Nevertheless, challenges persist in realizing ultra-fast full-size protein sensing, including loss of molecular integrity due to protein fragmentation, biases introduced by antibodies affinity, identification of proteoforms and low throughputs. Here, we introduce a single-molecule method for parallel protein separation and tracking, yielding multi-dimensional molecular properties used for their iden… Show more
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