Single-plane compensatory phase shift of head and eye oscillations in infantile nystagmus syndrome

Anagnostou, Evangelos; Spengos, Konstantinos; Anastasopoulos, D.

doi:10.1016/j.jns.2011.05.033

Cited by 2 publications

(3 citation statements)

References 15 publications

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“…In the other case, the VOR is not turned off, and hence the head oscillations are not adaptive but presumably a manifestation of an abnormality in the cephalomotor system. We recently discovered two types of head oscillations in INS patients [31] ; one type had 2-3 Hz frequency, consistent with previous observations [28-30] . The second novel subtype had the higher frequency in the range of 5-8 Hz [31] .…”

Section: Independent (Or Possibly Interdependent) Eye and Head Oscillsupporting

confidence: 88%

“…Most investigations revealed 2-3 Hz head oscillations in patients with INS [28-30] . A fundamental question has been: are these head oscillations in some way adaptive to compensate for the eye nystagmus or are they a pathological abnormality in the cephalomotor system much as is the eye nystagmus in INS is a pathological abnormality in the ocular motor system?…”

Section: Independent (Or Possibly Interdependent) Eye and Head Oscillmentioning

confidence: 99%

“…This interpretation was consistent with a previous proposal that even the low-frequency head oscillations reflect pathological reverberations in the cephalomotor system [28] . Other investigators, on the contrary, proposed that low-frequency head oscillations are the consequence of a central adaptive strategy to minimize nystagmus [29, 30, 32] . Much as the eye oscillations of the infantile nystagmus syndrome remain poorly understood, the same can be said for the head oscillations.…”

Section: Independent (Or Possibly Interdependent) Eye and Head Oscillmentioning

confidence: 99%

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Abnormal head oscillations in neuro-ophthalmology and neuro-otology

Shaikh

2016

Current Opinion in Neurology

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Purpose This paper describes the clinical phenomenology and contemporary pathophysiology of concurrent oscillations of the eyes and the head that are present in neurological conditions with diverse etiologies. Recent findings One classic example is spasmus nutans in which the eye oscillations are the primary pathology while head nodding is thought to be an operant conditional response that suppresses the eye oscillations to facilitate clear vision. The second example is a combination of head tremor and inadequate compensatory eye movements due to vestibular hypofunction leading to the illusion of pendular nystagmus – hence the condition is called pseudonystagmus. Cerebellar degeneration in ataxia-telangiectasia or synchronized spontaneous discharge from the inferior olive and cerebellum in the syndrome of ocular palatal tremor with dystonia are examples of eye and head oscillations due to the impairment in cerebellar outflow. Infantile nystagmus syndrome also presents with eye and head oscillations, but here the relationship between the two types of oscillations differs among patients and is still unclear. Summary The clinical features and putative pathophysiology of diverse disorders of the eyes and head that produce unwanted oscillations are reviewed and some analogies between eye and head oscillations are suggested. Key clinical pearls that are essential to separate these disorders at the bedside are also emphasized.

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Section: Independent (Or Possibly Interdependent) Eye and Head Oscillsupporting

confidence: 88%

Section: Independent (Or Possibly Interdependent) Eye and Head Oscillmentioning

confidence: 99%