Abstract:Establishing the biological basis of cognition and its disorders will require high precision spatiotemporal measurements of neural activity. Recently developed genetically encoded voltage indicators (GEVIs) report both spiking and subthreshold activity of identified neurons. However, maximally capitalising on the potential of GEVIs will require imaging at the millisecond time scales, which remains challenging with standard camera systems. Here we report application of single photon avalanche diode (SPAD) senso… Show more
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