Single photon emission computed tomography (<scp>SPECT</scp>) and <scp>SPECT</scp>/low‐dose computerized tomography did not increase sensitivity or specificity compared to planar bone scintigraphy for detection of bone metastases in advanced breast cancer

Haraldsen, Ate; Bluhme, Henrik; Røhl, Lisbeth; Pedersen, Erik Morre; Jensen, Anders Bonde; Hansen, Eva Boysen; Nellemann, Hanne; Rasmussen, Finn

doi:10.1111/cpf.12191

Cited by 12 publications

(6 citation statements)

References 16 publications

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“…Unlike the above cited authors, Haraldsen (ref. 29 ) found no substantial improvement of the SPECT/low dose CT diagnosis of bone metastases in breast cancer compared to the whole-body planar scan but the sample size was small. Haraldsen reported sensitivity of SPECT/ low dose CT 79% only, in contrast with sensitivity of whole-body planar scan 87%.…”

Section: Detection Of Bone Metastasesmentioning

confidence: 92%

SPECT/CT imaging in breast cancer - current status and challenges

Simanek

Koranda²

2016

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Background. The increasing incidence of breast cancer worldwide raises the importance of improving imaging techniques for disease stratification after early lesion detection. SPECT/CT imaging is now widely available but its diagnostic potential is not fully utilized for more specific purposes including breast cancer patient stratification. Methods and Results. A Pubmed search for both original and review articles related to the value of SPECT/CT in breast cancer patients and comparison to other diagnostic methods. 62 articles were found using the key words SPECT/CT, Fusion Image and Breast Cancer. Development of a new generation of SPECT/CT systems and their introduction into practice has changed the old diagnostic algorithm. The increasing importance of SPECT/CT in the detection of bone metastases is confirmed. The diagnostic accuracy of new SPECT/CT instruments in the diagnostics of bone metastases is nearly comparable to PET/CT scans. SPECT/CT is more widely available and costs less than PET. It is able not only to identify a sentinel lymph nodes in atypical localizations but also to detect sentinel lymph nodes non visualized on previous planar scans. SPECT/CT offers precise anatomic localization of sentinel lymph nodes, thereby facilitating surgery. Knowledge of precise sentinel lymph node localization can also be applied in radiotherapy. Conclusions. The role of hybrid SPECT/CT imaging in breast cancer patients is changing. It is a powerful modality for skeletal and nodal staging in breast cancer patients with important impact on therapy.

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Section: Detection Of Bone Metastasesmentioning

confidence: 92%

SPECT/CT imaging in breast cancer - current status and challenges

Simanek

Koranda²

2016

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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“…Результати дослідження ОФЕКТ/КT кісткової системи зазвичай мають не дуже високу специфічність [14,39]. В даному контексті NaF-ПЕТ візуалізація є безумовним кроком уперед.…”

Section: перспективи застосування кількісних параметрів офект кісток unclassified

Перспективы Количественной Оценки Результатов Однофотонной Эмиссионной Компьютерной Томографии Костной Системы (Обзор Литературы)

Korol¹,

Samokhin²,

Ткаченко³

2021

TRAUMA

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В обзоре литературы рассмотрены вопросы перспективы количественной оценки результатов однофотонной эмиссионной компьютерной томографии (ОФЭКТ) костной системы. Синтез функциональной информации, полученной с помощью ОФЭКТ в комплексе с высоким разрешением КТ, позволяет эффективно определять патологический метаболизм в костях с одновременной оценкой сосуществующих структурных изменений. Показатели максимального процента стандартизированного накопления (ПСН) радиофармпрепарата (РФП) и пикового процента стандартизированного накопления следует считать наиболее оптимальными параметрами количественного определения фокального поглощения РФП. В дальнейшем необходимо привлекать более узкие подгруппы больных (например, по возрасту, росту, массе, полу и т.д.), имеющих специфические условия, для того чтобы создать соответствующую доказательную базу. Однако необходимы дальнейшие технологические усовершенствования для того, чтобы расчет количественных параметров ОФЭКТ путем вычисления ПСН стал частью обычной медицинской практики.

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“…Claustrophobia is one of the most common phobias experienced by both men and women around the world, which leads some patients preferring not to choose such devices [19]. Specificity (%) 98.5 [23] 96.9 [23] 80.7 [30] 88.5 [35] 89.7 [40] 85 [45] 89 [49] 71.4 [53] 87 [58] 96 [62] 59.5 [67] 71 [72] 89.4 [78] Sensitivity (%) 66.1 [23] 69.1 [23] 92 [30] 72.6 [35] 82 [41] 90 [45] 95 [49] 100 [53] 91 [58] 95 [63] 96.4 [67] 87 [72] 95.6 [78] Total Scan Time 5 sec. [24] 6 sec.…”

Section: Jinst 15 C05029mentioning

confidence: 99%

Evaluation and simulation of breast cancer imaging devices using multi-criteria decision theory

Erdagli¹,

Ozsahin

Uzun³

2020

J. Inst.

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Breast cancer is the most common type of cancer seen in women. The incidence of breast cancer increases with age. The most important factor in breast cancer is that it is diagnosed before spreading to other organs by the blood or lymph circulation. When cancer is diagnosed at an early stage, the success rate of breast cancer treatment is over 90%. For this reason, breast cancer imaging devices should be used for early diagnosis of breast cancer. The main aim of this study is to shed more light on the parameters that affect the different imaging device alternatives for breast cancer and how these parameters affect the preference ranking of each imaging technique. In this study, the most commonly used imaging devices for breast cancer are analysed based on various parameters that are likely to affect the outcome of the imaging methods. These parameters are the cost per scan, cost of the device, radiation dose, specificity, sensitivity, total scan time, spatial resolution, comparison with the natural radiation exposure, real 3D, compression and claustrophobia. According to this study, positron emission mammography and breast computed tomography are the best breast cancer imaging techniques for both patients and hospitals. The analysis and ranking were evaluated and compared using fuzzy PROMETHEE, a multi-criteria decision-making technique. K: Computerized Tomography (CT) and Computed Radiography (CR); Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA); Medical-image reconstruction methods and algorithms, computer-aided diagnosis; X-ray mammography and scinto-and MRI-mammography 1Corresponding author.

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Single photon emission computed tomography (SPECT) and SPECT/low‐dose computerized tomography did not increase sensitivity or specificity compared to planar bone scintigraphy for detection of bone metastases in advanced breast cancer

Cited by 12 publications

References 16 publications

SPECT/CT imaging in breast cancer - current status and challenges

SPECT/CT imaging in breast cancer - current status and challenges

Перспективы Количественной Оценки Результатов Однофотонной Эмиссионной Компьютерной Томографии Костной Системы (Обзор Литературы)

Evaluation and simulation of breast cancer imaging devices using multi-criteria decision theory

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