Single-nucleotide polymorphisms link gout with health-related lifestyle factors in Korean cohorts
Hye Kyung Jeon,
Hae Young Yoo
Abstract:Gout—a very painful inflammatory arthritis caused by the deposition of monosodium urate crystals in the joints—is influenced by several factors. We identified the association of single- nucleotide polymorphisms (SNPs) that link gout with health-related lifestyle factors using genomic data from the Korean Genome and Epidemiology Study. We conducted a genome-wide association study (GWAS) on 18,927 samples of 438 Korean patients with gout and 18,489 controls for the discovery stage. For the replication stage, ano… Show more
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