The 22 Mg(α,p) 25 Al reaction rate has been identified as a major source of uncertainty for understanding the nucleosynthesis flow in Type-I x-ray bursts (XRBs). We report a direct measurement of the energy-and angle-integrated cross sections of this reaction in a 3.3-6.9 MeV center-of-mass energy range using the MUlti-Sampling Ionization Chamber (MUSIC). The new 22 Mg(α,p) 25 Al reaction rate is a factor of ∼4 higher than the previous direct measurement of this reaction within temperatures relevant for XRBs, resulting in the 22 Mg waiting point of x-ray burst nucleosynthesis flow to be significantly bypassed via the (α, p) reaction.