Single Intraperitoneal Injection of Low-Dose Ketamine Pretreatment Alleviates Mechanical Hyperalgesia and Downregulates the Expression of Inflammatory Cytokines in Spinal Dorsal Horn of Rats
Abstract:Single intraperitoneal injection of low-dose ketamine pretreatment alleviates mechanical hyperalgesia and downregulates the expression of inflammatory cytokines in spinal dorsal horn of rats after skin/muscle incision and retraction. J Anesth Perioper Med 2015; 2: 236-43.Background: Various common surgeries, such as thoracotomy and inguinal hernia repair which involve essential prolonged tissue retraction, often evoke chronic postoperative pain (CPOP). They bring great pain to patients, and make the qualities … Show more
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